Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758488 | 0.82 | LPAR1 (0.44) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL12846144 | 0.79 | GAA (0.49) | EPHX1 | |
| SCHEMBL26755912 | 0.78 | LPAR1 (0.55) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL17753845 | 0.78 | LPAR1 (0.46) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL14090771 | 0.76 | LPAR1 (0.41) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL17758486 | 0.76 | LPAR2 (0.45) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL12716923 | 0.76 | LPAR2 (0.46) | LPAR1LPAR2ENPP2LPAR3MMP1 | |
| SCHEMBL17753978 | 0.76 | LPAR1 (0.64) | LPAR1LPAR2ENPP2LPAR3 | |
| SCHEMBL3239278 | 0.75 | LPAR2 (0.44) | LPAR1LPAR2ENPP2LPAR3CA12 | |
| SCHEMBL4098549 | 0.75 | SAT1 (0.53) | LPAR1LPAR2ENPP2LPAR3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | VOCO GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115108-A1 | POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT | CAD, PCBP1, PPIP5K2 | LPAR1 2921/4885LPAR2 2660/4885ENPP2 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.