SCHEMBL5334826

SCHEMBL5334826

COC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ALDH1A1 P00352 3/20 0.43
NPSR1 Q6W5P4 2/20 0.42
NR4A2 P43354 1/20 0.41
KDM4E B2RXH2 3/20 0.40
CYP3A4 P08684 2/20 0.39
ACHE P22303 1/20 0.39
TSHR P16473 4/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 2/20 0.38
GLA P06280 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339188 0.94 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL7202434 0.92 CA12 (0.44) CA12CA1CA2CA7CA9
Dacthal SCHEMBL53477 0.92 CA12 (0.48) CA12CA1CA2CA7CA9
Dacthal SCHEMBL8827292 0.92 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL7756813 0.91 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL5336516 0.91 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL7074076 0.85 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL11696970 0.82 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL12921185 0.82 KDM4E (0.50) CA12CA1CA2CA7CA9
SCHEMBL1901154 0.82 TSHR (0.48) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2300256-A None JP disclosed
EP-3087155-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI Albemarle Corporation (US) 2016-11-02 EP disclosed
US-20160289527-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI ALBEMARLE CORP (US) 2016-10-06 US disclosed
WO-2015100004-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI ALBEMARLE CORPORATION (US) 2015-07-02 WO disclosed
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
US-7307041-B2 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA HEALTHCARE (BE) 2007-12-11 US disclosed
EP-1637338-B1 Substantially light-insensitive thermographic recording material AGFA GEVAERT (BE) 2007-04-04 EP disclosed
US-20060063670-A1 Stabilizers for use in substantially light-insensitive thermographic recording materials AGFA-GEVAERT (BE) 2006-03-23 US disclosed
EP-1637338-A1 Substantially light-insensitive thermographic recording material Agfa-Gevaert (BE) 2006-03-22 EP disclosed
WO-1981000572-A1 SUSPENSION POLYMERIZATION PROCESS FOR MAKING VINYL RESINS FOR USE IN PLASTISOL GOODRICH CO B F (US) 1981-03-05 WO disclosed
EP-0020521-A4 USE OF AN ELECTROLYTE IN THE EMULSION POLYMERIZATION PROCESS FOR PRODUCING VINYL DISPERSION RESINS. GOODRICH CO B F (US) 1981-02-24 EP disclosed
EP-0020521-A1 USE OF AN ELECTROLYTE IN THE EMULSION POLYMERIZATION PROCESS FOR PRODUCING VINYL DISPERSION RESINS The B.F. GOODRICH Company (US) 1981-01-07 EP disclosed
WO-1980000967-A1 USE OF AN ELECTROLYTE IN THE EMULSION POLYMERIZATION PROCESS FOR PRODUCING VINYL DISPERSION RESINS GOODRICH CO B F (US) 1980-05-15 WO disclosed
EP-0007641-A2 Process for producing homopolymers or copolymers of vinyl or vinylidene halides by emulsion polymerization The B.F. GOODRICH Company (US) 1980-02-06 EP disclosed
US-4186259-A PREVENTION OF POLYMER BUILDUP IN REACTOR THE B. F. GOODRICH COMPANY (US) 1980-01-29 US disclosed
US-4076920-A FREE RADICAL CATALYSTS THE B. F. GOODRICH COMPANY (US) 1978-02-28 US disclosed
US-4029687-A HERBICIDES CIBA-GEIGY AG (CH) 1977-06-14 US disclosed
US-4004914-A HERBICIDES CIBA-GEIGY AG (CH) 1977-01-25 US disclosed
US-3935173-A POLYESTER TYPE OLIGO(METH) ACRYLATE TOAGOSEI CHEMICAL INDUSTRIAL CO. LTD. (JA) 1976-01-27 US disclosed