Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465867 | 0.82 | — | — | |
| SCHEMBL4859997 | 0.82 | — | — | |
| SCHEMBL6009854 | 0.67 | — | — | |
| Iodide SCHEMBL18663295 | 0.67 | — | — | |
| Lithium Ion SCHEMBL4307118 | 0.67 | — | — | |
| Potassium Ion SCHEMBL4913019 | 0.67 | — | — | |
| Potassium Ion SCHEMBL9658126 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL438334 | 0.67 | — | — | |
| Potassium Ion SCHEMBL6041128 | 0.67 | — | — | |
| Potassium Ion SCHEMBL7722887 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203940-A1 | Method for preparing 4-[2-(dimethylamino)ethoxy]benzylamine as itopride-hydrocloride salt mediate | IL-YANG PHARM. CO., LTD. (KR) | 2009-08-13 | — | — | US | disclosed |
| EP-1771408-A4 | METHOD FOR PREPARING 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE AS ITOPRIDE HYDROCLORIDE SALT MEDIATE | IL YANG PHARM CO LTD (KR) | 2007-08-29 | — | — | EP | disclosed |
| EP-1771408-A1 | METHOD FOR PREPARING 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE AS ITOPRIDE HYDROCLORIDE SALT MEDIATE | Il Yang Pharm. Co. Ltd. (KR) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006011696-A1 | METHOD FOR PREPARING 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE AS ITOPRIDE HYDROCLORIDE SALT MEDIATE | IL YANG PHARM. CO., LTD (KR) | 2006-02-02 | — | — | WO | disclosed |