SCHEMBL4098387

SCHEMBL4098387

O=C(O)c1cccc2c(Cl)cccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.63
ALDH1A1 P00352 4/20 0.61
NR4A2 P43354 2/20 0.57
NR4A1 P22736 1/20 0.57
NR4A3 Q92570 1/20 0.57
CYP1A2 P05177 2/20 0.56
CYP2A6 P11509 1/20 0.56
KMT2A Q03164 4/20 0.53
KDM4E B2RXH2 3/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
PKM P14618 1/20 0.53
HTT P42858 1/20 0.53
ATM Q13315 1/20 0.52
PBRM1 Q86U86 2/20 0.49
HAVCR2 Q8TDQ0 1/20 0.49
ALOX15 P16050 1/20 0.48
CES2 O00748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6915204 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6909416 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6915995 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6913041 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6915043 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6909419 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6913045 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6915652 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6912784 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3
SCHEMBL6915042 0.98 TSHR (0.61) TSHRALDH1A1NR4A2NR4A1NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115954444-B Preparation method of naphthalene polycarboxylate organic material and application of naphthalene polycarboxylate organic material in metal ion battery 中国科学院深圳先进技术研究院 2025-01-14 CN disclosed
WO-2023277630-A1 GALACTOSIDE DERIVATIVE AS GALECTIN-3 INHIBITOR 주식회사 티움바이오 2023-01-05 WO disclosed
US-9447054-B2 Anticancer supplement agent including benzo[D]oxazol derivative as effective ingredient KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2016-09-20 US disclosed
US-9447054-B2 Anticancer supplement agent including benzo[D]oxazol derivative as effective ingredient KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2016-09-20 US disclosed
US-9447054-B2 Anticancer supplement agent including benzo[D]oxazol derivative as effective ingredient KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2016-09-20 US disclosed
US-20150197498-A1 ANTICANCER SUPPLEMENT AGENT INCLUDING BENZO[D]OXAZOL DERIVATIVE AS EFFECTIVE INGREDIENT KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2015-07-16 US disclosed
US-20150197498-A1 ANTICANCER SUPPLEMENT AGENT INCLUDING BENZO[D]OXAZOL DERIVATIVE AS EFFECTIVE INGREDIENT KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2015-07-16 US disclosed
US-20150197498-A1 ANTICANCER SUPPLEMENT AGENT INCLUDING BENZO[D]OXAZOL DERIVATIVE AS EFFECTIVE INGREDIENT KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) 2015-07-16 US disclosed
US-20150150852-A1 TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS SIGA TECHNOLOGIES, INC. (US) 2015-06-04 US disclosed
US-8993604-B2 Treatment and prevention of dengue virus infections SIGA TECHNOLOGIES, INC. (US) 2015-03-31 US disclosed
CN-101155817-A Dihydroimidazothiazole derivatives PROSIDION LTD (GB) 2008-04-02 CN disclosed
EP-1851232-A2 DIHYDROIMIDAZOTHIAZOLE DERIVATIVES Prosidion Limited (GB) 2007-11-07 EP disclosed
WO-2006085118-A2 DIHYDROIMIDAZOTHIAZOLE DERIVATIVES PROSIDION LIMITED (GB) 2006-08-17 WO disclosed
US-20060128823-A1 Radiation curable inkjet recording ink, and method of producing planographic printing plate using same, and ink composition, inkjet recording method, printed material, method of producing a planographic printing plate, and planographic printing plate FUJI PHOTO FILM CO., LTD. 2006-06-15 US disclosed
EP-1657286-A2 Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye FUJI PHOTO FILM CO., LTD. (JP) 2006-05-17 EP disclosed
US-6982348-B2 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-03 US disclosed
US-20040127574-A1 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-07-01 US disclosed
EP-1362846-A1 AMINOETHANOL DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2003-11-19 EP disclosed
US-4224225-A PHOTOPOLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1980-09-23 US disclosed
US-4036838-A Process for the production of nitro derivatives of aromatic compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150150852-A1 TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS HAVCR2, TTPA, CHIA TSHR 3237/4885ALDH1A1 899/4885NR4A2 611/4885
US-20040127574-A1 Aminoethanol derivatives CETP, LCAT, MTTP TSHR 3729/4885ALDH1A1 783/4885NR4A2 649/4885
US-20150197498-A1 ANTICANCER SUPPLEMENT AGENT INCLUDING BENZO[D]OXAZOL DERIVATIVE AS EFFECTIVE INGREDIENT NFE2L2, KEAP1, OXA1L TSHR 4516/4885ALDH1A1 425/4885NR4A2 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.