SCHEMBL4098717

SCHEMBL4098717

CC(CC(=O)O)(C(F)(F)F)P(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.41
CHRM1 P11229 1/20 0.41
TBXA2R P21731 1/20 0.41
ADRA1A P35348 1/20 0.41
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
PGK1 P00558 2/20 0.36
PGK2 P07205 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
FFAR1 O14842 1/20 0.35
CPT2 P23786 1/20 0.35
ACLY P53396 2/20 0.34
LMNA P02545 2/20 0.33
FDPS P14324 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779201 0.73 PGK1 (0.39) PGK1PGK2LMNAFDPSLPAR1
SCHEMBL10903812 0.72 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL3457861 0.70 HMGCR (0.52) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL2301499 0.69 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL10361611 0.68 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL871609 0.68 TSHR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL9308664 0.68 FDPS (0.46) HMGCRCHRM1TBXA2RADRA1ACYP2C19
Ammonia Solution, Strong SCHEMBL10361614 0.68 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL781232 0.68 PGK1 (0.48) PGK1PGK2LMNAFDPSLPAR1
SCHEMBL16269785 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293029-B2 Colored conversion layers on metal surfaces HENKEL AG & CO. KGAA (DE) 2012-10-23 US disclosed
US-20090214883-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION HENKEL AG & CO. KGAA (DE) 2009-08-27 US disclosed
US-20060173099-A1 Colored conversion layers on metal surfaces HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-08-03 US disclosed