Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302248 | 1.00 | ALDH1A1 (0.62) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL3145765 | 1.00 | ALDH1A1 (0.62) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL19527551 | 0.88 | ALDH1A1 (0.49) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL19527542 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GLASMN1; SMN2KDM4EGAA | |
| SCHEMBL11695226 | 0.85 | ALDH1A1 (0.60) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL22357196 | 0.83 | ALDH1A1 (0.78) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL679937 | 0.83 | ALDH1A1 (0.78) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL1155048 | 0.83 | KDM4E (0.49) | ALDH1A1GLASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8707600 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| SCHEMBL19527607 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1TDP1SMN1; SMN2TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116801872-A | Methods of modulating androgen receptor coacervates | 上海奕拓医药科技有限责任公司 | 2023-09-22 | — | — | CN | claimed |
| WO-2022171163-A1 | METHODS OF MODULATING ANDROGEN RECEPTOR CONDENSATES | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2022-08-18 | — | — | WO | claimed |
| CN-118269451-A | Ultralight high-resilience damping and sound-absorbing cotton and production process thereof | 保定跃飞新型吸音材料有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-116801872-A | Methods of modulating androgen receptor coacervates | 上海奕拓医药科技有限责任公司 | 2023-09-22 | — | — | CN | disclosed |
| US-11639330-B2 | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | SHOWA DENKO K.K. (JP) | 2023-05-02 | — | — | US | disclosed |
| US-11639330-B2 | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | SHOWA DENKO K.K. (JP) | 2023-05-02 | — | — | US | disclosed |
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |
| WO-2022171163-A1 | METHODS OF MODULATING ANDROGEN RECEPTOR CONDENSATES | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |
| WO-2021131961-A1 | FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM | 昭和電工株式会社 | 2021-07-01 | — | — | WO | disclosed |
| US-20210188766-A1 | FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM | SHOWA DENKO K.K. (JP) | 2021-06-24 | — | — | US | disclosed |
| US-20180161309-A1 | METHODS AND COMPOSITIONS INVOLVING (S)-BUCINDOLOL | ARCA BIOPHARMA, INC. | 2018-06-14 | — | — | US | disclosed |
| US-4167581-A | 1-ARYLOXY-3-(ACYLAMINO)ALKYLAMINO-2-PROPANOL ADRENERGIC BLOCKING, AGENTS AND CARDIAC STIMULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |
| US-4115409-A | CARDIOVASCULAR DISORDERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4029795-A | 4(2' Isoquinolin-1-one)piperidines | CIBA-GEIGY CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-4025646-A | ADRENERGIC BLOCKING AGENTS, HYPOTENSIVES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-24 | — | — | US | disclosed |
| US-4016286-A | Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and their use as adrenolytics and hypotensives | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4000287-A | HYPOTENSIVES, ANTIARRHYTHMIC | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3975539-A | B-ADRENERGIC BLOCKING, HYPOTENSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3961071-A | CARDIOVASCULAR DISORDERS, 1-PHENOXY-2-HYDROXY-3-TERT-BUTYLAMINO PROPANES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-06-01 | — | — | US | disclosed |
| US-3959338-A | BETA-ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE | BOEHRINGER INGELHEIM GMBH | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161309-A1 | METHODS AND COMPOSITIONS INVOLVING (S)-BUCINDOLOL | ADRB3, ADRB2, ADRB1 | ALDH1A1 1011/4885GLA 2703/4885TDP1 2218/4885 |
| US-11639330-B2 | Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium | AFF1, PHOSPHO1, CHRM1 | ALDH1A1 3194/4885GLA 2717/4885TDP1 1177/4885 |
| US-20210188766-A1 | FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM | AFF1, PHOSPHO1, CHRM1 | ALDH1A1 3194/4885GLA 2717/4885TDP1 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.