Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950901 | 0.85 | DRD2 (0.50) | LMNASMN1; SMN2ALDH1A1KMT2APPARG | |
| SCHEMBL3808251 | 0.85 | CYP4F2 (0.45) | MRGPRX4MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL11897975 | 0.84 | LMNA (0.45) | MAPTHTTLMNASMN1; SMN2CA12 | |
| SCHEMBL12569398 | 0.84 | KDM4E (0.62) | LMNAKMT2ACYP1A2CYP3A4TSHR | |
| SCHEMBL23935649 | 0.83 | PPARA (0.57) | PPARGPPARA | |
| SCHEMBL1415515 | 0.83 | PPARG (0.57) | CYP1A2CYP3A4PPARGPPARA | |
| SCHEMBL18782458 | 0.81 | DRD2 (0.48) | MRGPRX4MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL3817257 | 0.81 | TNKS2 (0.46) | MAPTHTTLMNASMN1; SMN2CA12 | |
| SCHEMBL10596755 | 0.80 | PPARA (0.66) | CYP1A2CYP3A4PPARGPPARA | |
| SCHEMBL7078432 | 0.80 | MRGPRX4 (0.46) | MRGPRX4MAPTHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221702-A1 | COMPOUNDS | IMPERIAL INNOVATIONS LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-1879562-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | Imperial Innovations Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006097744-A2 | PHENOL DERIVATIVES AND THEIR USE TO MODULATE PKB ACTIVITY | IMPERIAL INNOVATIONS LIMITED (GB) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221702-A1 | COMPOUNDS | NCEH1, NME2, HRH3 | AKT1 33/4885MRGPRX4 1577/4885MAPT 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.