Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338983 | 0.89 | KMT2A (0.56) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL6342730 | 0.88 | P2RX7 (0.62) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL21715259 | 0.70 | MAPT (0.52) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL30314462 | 0.70 | MAPT (0.52) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL1225656 | 0.69 | POLB (0.51) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL1224861 | 0.68 | POLB (0.50) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL7058244 | 0.67 | POLB (0.49) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL1224424 | 0.67 | ENPP3 (0.54) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL4119358 | 0.65 | KMT2A (0.43) | P2RX7KMT2AMEN1LMNAPOLB | |
| SCHEMBL4097692 | 0.65 | PTGDR2 (0.51) | P2RX7KMT2AMEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064422-A2 | HEPATOCYTE GROWTH FACTOR PATHWAY ACTIVATORS IN FIBROTIC CONNECTIVE TISSUE DISEASES | ANGION BIOMEDICA CORP. (US) | 2009-05-22 | — | — | WO | disclosed |