Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097692 | 0.88 | PTGDR2 (0.51) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL4119358 | 0.85 | KMT2A (0.43) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL1224344 | 0.83 | KMT2A (0.47) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL6338983 | 0.76 | KMT2A (0.56) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL1225656 | 0.71 | POLB (0.51) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL1224861 | 0.71 | POLB (0.50) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL1224424 | 0.69 | ENPP3 (0.54) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL4099363 | 0.67 | P2RX7 (0.51) | POLBKMT2AMEN1P2RX7MAPT | |
| SCHEMBL7495596 | 0.67 | MAPK1 (0.63) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL1225291 | 0.67 | TSHR (0.54) | POLBKMT2AMEN1P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216459-A1 | Small-molecule modulators of hepatocyte growth factor / scatter factor activities | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2003-11-20 | — | — | US | disclosed |
| US-6589997-B2 | 1-Phenylprop-2-en-1-one derivatives as wound healing, anticarcinogenic, antiarthritic, antitumor, antiproliferative, antiinflammatory or antimetastasis agents | NORTH SHORE-LONG ISLAND JEWISH HEALTH SYSTEM | 2003-07-08 | — | — | US | disclosed |
| US-20030045559-A1 | Small-molecule modulators of hepatocyte growth factor / scatter factor activities | NORTH SHORE-LONG ISLAND JEWISH HEALTH SYSTEM | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045559-A1 | Small-molecule modulators of hepatocyte growth factor / scatter factor activities | HGF, HDGF, MET | POLB 2271/4885KMT2A 4257/4885MEN1 3250/4885 |
| US-20030216459-A1 | Small-molecule modulators of hepatocyte growth factor / scatter factor activities | HGF, HDGF, MET | POLB 2271/4885KMT2A 4257/4885MEN1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.