Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849730 | 1.00 | AKR1C4 (0.39) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL4103087 | 1.00 | AKR1C4 (0.39) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL13849728 | 0.82 | ALDH1A1 (0.40) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL4087942 | 0.80 | ACE2 (0.35) | ALDH1A1POLBTDP1 | |
| SCHEMBL5506589 | 0.80 | SLC6A12 (0.36) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL10780374 | 0.79 | AKR1C4 (0.35) | AKR1C4AKR1C3AKR1C2SLC6A12SLC6A11 | |
| SCHEMBL13845758 | 0.77 | CNR2 (0.33) | TDP1HIF1AEPAS1 | |
| SCHEMBL22795135 | 0.77 | CNR2 (0.33) | TDP1HIF1AEPAS1 | |
| SCHEMBL13845753 | 0.77 | CNR2 (0.33) | TDP1HIF1AEPAS1 | |
| SCHEMBL4858485 | 0.72 | POLB (0.43) | MAPTALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | SAN-EI GEN F.F.I. INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1787975-A1 | PROCESSES FOR PRODUCTION OF WINE LACTONE AND ITS INTERMEDIATES AND APPLICATION OF THE LACTONE | SAN-EI GEN F.F.I., INC. (JP) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118157-A1 | Processes For Production Of Wine Lactone And Its Intermediates And Application Of The Lactone | DCXR, COASY, AKR7A2 | AKR1C4 6/4885AKR1C3 17/4885AKR1C2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.