Acetophenone

Acetophenone

SCHEMBL4099795

CC(=O)c1ccccc1.CNC(C)C

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
LMNA P02545 3/20 0.53
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HPGD P15428 4/20 0.48
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 6/20 0.47
MEN1 O00255 3/20 0.47
CES1 P23141 2/20 0.46
CES2 O00748 1/20 0.46
TSHR P16473 2/20 0.45
HTR2A P28223 2/20 0.45
CYP3A4 P08684 2/20 0.45
ALOX15 P16050 2/20 0.45
CHRM2 P08172 1/20 0.45
ADRA1A P35348 1/20 0.45
RGS12 O14924 1/20 0.45
GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL28598165 0.86 MAPT (0.62) MAPTSMN1; SMN2LMNARAB9ANPC1
Acetophenone SCHEMBL329243 0.86 MAPT (0.62) MAPTSMN1; SMN2LMNARAB9ANPC1
Benzoic Acid SCHEMBL4096880 0.84 TSHR (0.64) MAPTSMN1; SMN2LMNARAB9AHPGD
Acetophenone SCHEMBL25382045 0.84 SMN1; SMN2 (0.60) MAPTSMN1; SMN2LMNARAB9ANPC1
Acetophenone SCHEMBL28762993 0.84 MAPT (0.60) MAPTSMN1; SMN2LMNARAB9ANPC1
Acetophenone SCHEMBL10608667 0.84 MAPT (0.60) MAPTSMN1; SMN2LMNARAB9ANPC1
Acetophenone SCHEMBL30537000 0.83
Acetophenone SCHEMBL30537005 0.83
Acetophenone SCHEMBL737 0.83
Acetophenone SCHEMBL1450855 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491915-B1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO LTD (JP) 2019-07-03 EP disclosed
US-8362105-B2 Dental curable composition and kit for such dental curable composition SUN MEDICAL CO., LTD. (JP) 2013-01-29 US disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20090258966-A1 Dental Composition NIHON UNIVERSITY (JP) 2009-10-15 US disclosed
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SUN MEDICAL CO., LTD. (JP) 2009-05-28 US disclosed
EP-1938781-A1 DENTAL CURABLE COMPOSITION AND KIT FOR SUCH DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2008-07-02 EP disclosed
EP-0923924-B1 Dental adhesive kit SUN MEDICAL CO LTD (JP) 2005-03-09 EP disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
US-6071983-A FOR TREATING TOOTH SURFACE BY FACILE HANDLING; FOR RESTORING A TOOTH-SURFACE WITH COATING MATERIAL OR RESTORING DENTAL RESTORATIVE RESINS SUN MEDICAL CO., LTD. (JP) 2000-06-06 US disclosed
EP-0684034-B1 Primer solution composition for dental bonding SUN MEDICAL CO LTD (JP) 2000-03-08 EP disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed
US-5834532-A BLEND OF POLYMERIZABLE MONOMER HAVING ACIDIC GROUPS AND AN INITIATOR SUN MEDICAL CO., LTD. (JP) 1998-11-10 US disclosed
US-5670559-A TREATMENT OF TEETH WITH COMPOUNDS OF IRON, COPPER AND COBALT SUN MEDICAL CO., LTD. (JP) 1997-09-23 US disclosed
US-5587406-A APPLYING CURABLE PRIMER COMPOSITION COMPRISING POLYMERIZABLE MONOMER HAVING ACID GROUP AND POLYMERIZABLE MONOMER HAVING HYDROXYL GROUP AND POLYMERIZATION INITIATOR TO TOOTH SUN MEDICAL CO., LTD. (JP) 1996-12-24 US disclosed
US-5530038-A CONTAINING UNSATURATED MONOMER WITH ACIDIC GROUP, UNSATURATED MONOMER WITH HYDROXYL GROUP, POLYMERIZATION INITIATOR, AMINE COMPOUND, ZIRCONIUM OXIDE AND ORGANIC COMPOSITE FILLERS SUN MEDICAL CO., LTD. (JP) 1996-06-25 US disclosed
EP-0684034-A1 Primer solution composition for dental bonding SUN MEDICAL CO., LTD. (JP) 1995-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258966-A1 Dental Composition DCPS, MMAB, CAD MAPT 592/4885SMN1; SMN2 4222/4885LMNA 2381/4885
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 MAPT 1563/4885SMN1; SMN2 1290/4885LMNA 740/4885
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SETDB1, SETD1B, SETD2 MAPT 1399/4885SMN1; SMN2 2593/4885LMNA 2339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.