Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | CLPP | Q16740 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937123 | 0.92 | RAB9A (0.67) | RAB9ANPC1ATMPROKR1MAPT | |
| SCHEMBL2937126 | 0.92 | RAB9A (0.67) | RAB9ANPC1ATMPROKR1MAPT | |
| SCHEMBL21425235 | 0.86 | PROKR1 (0.53) | RAB9ANPC1ATMPROKR1MAPT | |
| SCHEMBL3312540 | 0.85 | ALDH1A1 (0.62) | RAB9ANPC1ATMPROKR1MAPT | |
| SCHEMBL8288429 | 0.84 | ATM (0.74) | RAB9ANPC1ATMPROKR1ALDH1A1 | |
| SCHEMBL23854774 | 0.84 | ALDH1A1 (0.50) | PROKR1MAPTALDH1A1GAALMNA | |
| SCHEMBL9509660 | 0.84 | PROKR1 (0.60) | RAB9ANPC1PROKR1MAPTALDH1A1 | |
| SCHEMBL3737773 | 0.84 | ALDH1A1 (0.48) | RAB9ANPC1PROKR1MAPTALDH1A1 | |
| SCHEMBL2552810 | 0.84 | ALDH1A1 (0.50) | PROKR1MAPTALDH1A1GAALMNA | |
| SCHEMBL1995415 | 0.84 | ALDH1A1 (0.48) | RAB9ANPC1PROKR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186874-A1 | Carboxamide derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186874-A1 | Carboxamide derivative and use thereof | NTSR2, NTSR1, CNR2 | RAB9A 4001/4885NPC1 1521/4885ATM 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.