Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040386 | 0.97 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Methylamine SCHEMBL27579793 | 0.94 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL28482601 | 0.88 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Zinc Chloride SCHEMBL28046268 | 0.88 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11204122 | 0.80 | RAPGEF4 (0.40) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL10880511 | 0.80 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL8384844 | 0.76 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL26617131 | 0.76 | KMT2A (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6741463 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL11208413 | 0.73 | RAPGEF4 (0.34) | RAPGEF4CA1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5210 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253721-B | N- (4-indolyl) -N' -alkyl imidazole salt and application thereof | 昆明理工大学 | 2024-05-14 | — | — | CN | claimed |
| US-11926758-B2 | Polytriazole coating materials for metal substrates | SAUDI ARABIAN OIL COMPANY (SA) | 2024-03-12 | — | — | US | claimed |
| CN-117486780-A | 1-benzyl isatin derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2024-02-02 | — | — | CN | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| US-11814473-B2 | Polytriazole copolymer compositions | SAUDI ARABIAN OIL COMPANY (SA) | 2023-11-14 | — | — | US | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| EP-3606528-B1 | TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF | BROAD INST INC (US) | 2023-10-18 | — | — | EP | claimed |
| CN-111051288-B | Industrial process for monoalkylating piperidine nitrogen in piperidine derivatives with deuterated alkyl groups | 大塚制药株式会社 | 2023-08-25 | — | — | CN | claimed |
| CN-115974832-B | Disulfide bond-containing N-acetyl-L-cysteine derivative and preparation method and application thereof | 山东大学 | 2023-08-01 | — | — | CN | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| US-4228063-A | Flame-retardant, polyphenylene-ether resin compositions containing a 2,5,5-trisubstituted 1,3,2-dioxaphosphorinane-2-oxide | AMERICAN CYANAMID COMPANY (US) | 1980-10-14 | — | — | US | claimed |
| EP-0010347-A1 | Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
| US-4167630-A | Process for epimerizing beta-lactam antibiotic compounds, and related products | MERCK & CO., INC. (US) | 1979-09-11 | — | — | US | claimed |
| US-4162278-A | Flame retardant polyphenylene ether resin compositions containing a pentaerythrityl phosphonate | AMERICAN CYANAMID COMPANY (US) | 1979-07-24 | — | — | US | claimed |
| US-4107432-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-08-15 | — | — | US | claimed |
| US-4058661-A | 7-Diacyl cephalosporins | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | claimed |
| US-4053286-A | ACYLATION | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | claimed |
| US-4051132-A | Process for epimerizing beta-lactam antibiotic compounds by means of an acid quench | MERCK & CO., INC. (US) | 1977-09-27 | — | — | US | claimed |
| US-4014873-A | Process for the production of 7-acylamidocephalosporins | MERCK & CO., INC. (US) | 1977-03-29 | — | — | US | claimed |