Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845752 | 0.87 | RPS6KA3 (0.46) | MAPTKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL4296230 | 0.74 | HSD17B10 (0.61) | MAPTKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL3989046 | 0.73 | FAAH (0.46) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9669651 | 0.69 | RAB9A (0.58) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9771942 | 0.68 | MAPT (0.59) | MAPTKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL9052063 | 0.67 | NPC1 (0.53) | MAPTKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL9669437 | 0.67 | RAB9A (0.59) | MAPTKMT2AALDH1A1LMNANPC1 | |
| SCHEMBL24450206 | 0.67 | HDAC3 (0.58) | MAPTLMNARAB9ASMN1; SMN2CNR2 | |
| SCHEMBL10143997 | 0.66 | SMN1; SMN2 (0.53) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9669468 | 0.66 | NPC1 (0.54) | MAPTKMT2AALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060215-A1 | POLYAMIDES | SPIROGEN LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |