SCHEMBL4100519

SCHEMBL4100519

CC1(C(=O)Oc2cccc3ccccc23)CC2C=CC1C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
P2RX7 Q99572 1/20 0.44
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 3/20 0.44
PGR P06401 1/20 0.44
GAA P10253 1/20 0.44
PTGS1 P23219 1/20 0.44
MAPK1 P28482 1/20 0.44
HPGD P15428 3/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
CETP P11597 1/20 0.39
FABP7 O15540 4/20 0.38
FABP3 P05413 4/20 0.38
FABP5 Q01469 4/20 0.38
ALOX5 P09917 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4103952 0.75 KMT2A (0.43) KMT2ARAB9AMEN1P2RX7ALDH1A1
SCHEMBL15611957 0.74 KMT2A (0.42) KMT2ARAB9AMEN1L3MBTL1ALDH1A1
SCHEMBL14494462 0.74 KMT2A (0.41) KMT2ARAB9AMEN1L3MBTL1ALDH1A1
SCHEMBL13004857 0.72 KDM4E (0.63) KMT2ARAB9AMEN1L3MBTL1ALDH1A1
SCHEMBL18938394 0.71 P2RX7 (0.41) KMT2AMEN1P2RX7ALDH1A1NPSR1
SCHEMBL200115 0.71 P2RX7 (0.41) KMT2AMEN1P2RX7ALDH1A1NPSR1
SCHEMBL2899391 0.71 KMT2A (0.42) KMT2ARAB9AL3MBTL1P2RX7ALDH1A1
SCHEMBL28735245 0.71 ALDH1A1 (0.53) KMT2ARAB9AMEN1L3MBTL1ALDH1A1
SCHEMBL5456663 0.70 P2RX7 (0.39) P2RX7CETP
SCHEMBL31277438 0.70 P2RX7 (0.40) P2RX7CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090209705-A1 THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM JSR CORPORATION (JP) 2009-08-20 US disclosed
EP-1795559-A1 THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM JSR Corporation (JP) 2007-06-13 EP disclosed