SCHEMBL2899391

SCHEMBL2899391

CC1(OC(=O)c2cccc3ccccc23)CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
P2RX7 Q99572 1/20 0.40
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
CDC25B P30305 2/20 0.38
PLK1 P53350 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ADRB2 P07550 2/20 0.36
ADRB1 P08588 2/20 0.36
ADRB3 P13945 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MMP3 P08254 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2892925 0.83 ALDH1A1 (0.38) KMT2AP2RX7KDM4EALDH1A1HPGD
SCHEMBL202759 0.80 CDC25B (0.46) KMT2AP2RX7POLBGAACDC25B
SCHEMBL2893711 0.79 GAA (0.43) KMT2AGAAL3MBTL1
SCHEMBL2899258 0.78 MAPT (0.40) HRH3KDM4EALDH1A1ADRB2ADRB1
SCHEMBL2896199 0.75 PDCD1 (0.41) KMT2APOLBGAAKDM4EALDH1A1
SCHEMBL7863152 0.71 CYP2D6 (0.36) P2RX7
SCHEMBL18544158 0.71 PTPN1 (0.43) KMT2AP2RX7POLBNR4A1NR4A2
SCHEMBL2896267 0.70 HDAC3 (0.35) P2RX7POLBALDH1A1HDAC8
SCHEMBL4981052 0.69 KMT2A (0.40) KMT2APOLBGAANR4A1NR4A2
SCHEMBL29576322 0.68 TSHR (0.45) KMT2APOLBGAANR4A1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed