SCHEMBL4100798

SCHEMBL4100798

CC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@@]21C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.82
▸ MAPT P10636 3/20 0.82
▸ SMN1; SMN2 Q16637 3/20 0.82
▸ NPSR1 Q6W5P4 2/20 0.82
▸ NR3C1 P04150 7/20 0.68
▸ CYP3A4 P08684 5/20 0.68
▸ PGR P06401 4/20 0.68
▸ USP2 O75604 3/20 0.68
▸ NR1I2 O75469 2/20 0.68
▸ CYP2C9 P11712 2/20 0.68
▸ MLNR O43193 1/20 0.68
▸ ABCB11 O95342 1/20 0.68
▸ CYP3A5 P20815 1/20 0.68
▸ PPARG P37231 1/20 0.68
▸ CYP2D6 P10635 1/20 0.68
▸ MMP1 P03956 3/20 0.56
▸ ADORA3 P0DMS8 1/20 0.56
▸ DRD2 P14416 1/20 0.56
▸ OPRD1 P41143 1/20 0.56
▸ MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28099304 0.92 LMNA (0.88) LMNAMAPTSMN1; SMN2NPSR1NR3C1
SCHEMBL568167 0.92 LMNA (0.88) LMNAMAPTSMN1; SMN2NPSR1NR3C1
SCHEMBL5311083 0.91 LMNA (0.79) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL36599 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL11750078 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL448850 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL29572705 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL11124627 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL29410388 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1
Clobetasone Butyrate SCHEMBL14339619 0.90 LMNA (1.00) LMNAMAPTSMN1; SMN2NPSR1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106170285-A Comprise the pharmaceutical composition of antifungal and steroid 日本农药株式会社 2016-11-30 — — CN claimed
EP-1312356-B1 AQUEOUS SUSPENSION PREPARATIONS SENJU PHARMA CO (JP) 2012-10-17 — — EP claimed
US-20030195179-A1 Aqueous suspension preparations SENJU PHARMACEUTICAL CO., LTD. (JP) 2003-10-16 — — US claimed
EP-1312356-A1 AQUEOUS SUSPENSION PREPARATIONS Senju Pharmaceutical Co., Ltd. (JP) 2003-05-21 — — EP claimed
US-20230041642-A1 Aggregation Inhibitory Agent and Medical Composition and Medical Device Including Same NIPRO CORPORATION (JP) 2023-02-09 — — US disclosed
EP-4079325-A1 AGGREGATION INHIBITORY AGENT AND MEDICAL COMPOSITION AND MEDICAL DEVICE INCLUDING SAME Nipro Corporation (JP) 2022-10-26 — — EP disclosed
CN-114848506-A Multifunctional personalized patch with therapeutic properties 强生消费者公司 2022-08-05 — — CN disclosed
CN-110799156-B Multifunctional personalized patch with therapeutic properties 强生消费者公司 2022-05-24 — — CN disclosed
CN-113382730-A Selective glucocorticoid receptor modifiers for treatment of impaired skin wound healing 阿克里斯生物医药有限公司 2021-09-10 — — CN disclosed
EP-2484383-B1 METHOD FOR IMPROVING THE AQUEOUS SOLUBILITY OF POORLY-SOLUBLE SUBSTANCES SANGI KK (JP) 2021-04-28 — — EP disclosed
CN-112312898-A Three-dimensional microfluidic device for delivery of active substances 强生消费者公司 2021-02-02 — — CN disclosed
CN-112312892-A Three-dimensional microfluidic device for delivery of active substances 强生消费者公司 2021-02-02 — — CN disclosed
EP-2821084-A1 METHOD FOR IMPROVING WATER SOLUBILITY OF SLIGHTLY SOLUBLE SUBSTANCE Kabushiki Kaisha Sangi (JP) 2015-01-07 — — EP disclosed
US-8658703-B2 Aqueous suspension preparations SENJU PHARMACEUTICAL CO., LTD. (JP) 2014-02-25 — — US disclosed
US-20120264608-A1 Method for Improving the Aqueous Solubility of Poorly-Soluble Substances KABUSHIKI KAISHA SANGI (JP) 2012-10-18 — — US disclosed
EP-1312356-B1 AQUEOUS SUSPENSION PREPARATIONS SENJU PHARMA CO (JP) 2012-10-17 — — EP disclosed
EP-2484383-A1 METHOD FOR IMPROVING THE AQUEOUS SOLUBILITY OF POORLY-SOLUBLE SUBSTANCES KABUSHIKI KAISHA SANGI (JP) 2012-08-08 — — EP disclosed
US-20090253807-A1 AQUEOUS SUSPENSION PREPARATIONS SENJU PHARMACEUTICAL CO. LTD. (JP) 2009-10-08 — — US disclosed
US-20030195179-A1 Aqueous suspension preparations SENJU PHARMACEUTICAL CO., LTD. (JP) 2003-10-16 — — US disclosed
EP-1312356-A1 AQUEOUS SUSPENSION PREPARATIONS Senju Pharmaceutical Co., Ltd. (JP) 2003-05-21 — — EP disclosed
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