SCHEMBL4100839

SCHEMBL4100839

CCCCCCCC(O)C1=CC(C)OC1=O

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.50
EPAS1 Q99814 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18196027 1.00 HIF1A (0.50) HIF1AEPAS1
SCHEMBL1231200 1.00 HIF1A (0.50) HIF1AEPAS1
SCHEMBL21434328 1.00 HIF1A (0.50) HIF1AEPAS1
SCHEMBL8616760 0.86 PDCD4 (0.42) HIF1AEPAS1
SCHEMBL12315508 0.82 HIF1A (0.62) HIF1AEPAS1
SCHEMBL14500948 0.78 HIF1A (0.76) HIF1AEPAS1
SCHEMBL14500959 0.78 HIF1A (0.76) HIF1AEPAS1
SCHEMBL14500933 0.78 HIF1A (0.76) HIF1AEPAS1
SCHEMBL14500947 0.78 HIF1A (0.76) HIF1AEPAS1
SCHEMBL17867390 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-114555124-A Pharmaceutical co-crystal salt formulation 瑟拉诺沃控股有限公司 2022-05-27 CN disclosed
CN-114041068-A OFDM radar sensor system with actively forwarding repeaters 罗伯特·博世有限公司 2022-02-11 CN disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
US-20090192220-A1 TREATMENT FOR SOLID TUMORS ORE PHARMACEUTICALS INC. (US) 2009-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090192220-A1 TREATMENT FOR SOLID TUMORS ACAT2, ACAT1, APRT HIF1A 25/4885EPAS1 781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.