Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17025310 | 0.88 | NPBWR1 (0.49) | NPBWR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10195530 | 0.87 | NPBWR1 (0.51) | NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL14320783 | 0.83 | NPBWR1 (0.52) | NPBWR1MCHR1GRIN1GRIN2BKDM4E | |
| SCHEMBL4109782 | 0.77 | NPBWR1 (0.46) | NPBWR1MCHR1GRIN1GRIN2BDCTPP1 | |
| SCHEMBL4102442 | 0.77 | GRIN1 (0.39) | NPBWR1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20996061 | 0.77 | MAPT (0.41) | DCTPP1KDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL11936663 | 0.76 | MEN1 (0.44) | NPBWR1MCHR1GRIN1GRIN2BPKM | |
| SCHEMBL21383800 | 0.75 | NPBWR1 (0.49) | NPBWR1MCHR1DCTPP1PDE1APDE1B | |
| SCHEMBL30529333 | 0.75 | NPBWR1 (0.49) | NPBWR1MCHR1DCTPP1PDE1APDE1B | |
| SCHEMBL22892720 | 0.74 | NPBWR1 (0.51) | NPBWR1MCHR1GRIN1GRIN2BDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | NPBWR1 128/4885TUBB4A 4248/4885TUBB 4470/4885 |
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | HIF1AN, EGLN2, EGLN3 | NPBWR1 3313/4885TUBB4A 3916/4885TUBB 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.