Sugi Predict

Sugi Predict / Compounds / SCHEMBL410113

SCHEMBL410113

SCHEMBL410113

[O]C(=O)C=Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.70
▸ HDAC3 O15379 2/20 0.70
▸ HDAC4 P56524 2/20 0.70
▸ HDAC1 Q13547 2/20 0.70
▸ HDAC2 Q92769 2/20 0.70
▸ HDAC8 Q9BY41 2/20 0.70
▸ HDAC6 Q9UBN7 2/20 0.70
▸ PLIN1 O60240 2/20 0.70
▸ LMNA P02545 2/20 0.70
▸ RECQL P46063 2/20 0.70
▸ PLIN5 Q00G26 2/20 0.70
▸ ABHD5 Q8WTS1 2/20 0.70
▸ ALDH1A1 P00352 2/20 0.70
▸ F3 P13726 2/20 0.70
▸ TNKS O95271 1/20 0.70
▸ HCAR2 Q8TDS4 1/20 0.70
▸ HDAC7 Q8WUI4 1/20 0.70
▸ HDAC10 Q969S8 1/20 0.70
▸ HDAC11 Q96DB2 1/20 0.70
▸ TNKS2 Q9H2K2 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410112 1.00 MAPT (0.70) MAPTHDAC3HDAC4HDAC1HDAC2
Methacrylic Acid SCHEMBL29048486 0.86 TDP1 (0.60) MAPTHDAC3HDAC4HDAC1HDAC2
Bicarbonate SCHEMBL28255705 0.85 MAPT (0.95) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL28530481 0.84 HDAC3 (0.66) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL11688162 0.84 HDAC3 (0.66) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL11688156 0.84 HDAC3 (0.66) MAPTHDAC3HDAC4HDAC1HDAC2
(Z)-1,2-Diphenylethene SCHEMBL4532649 0.84 HDAC1 (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
(Z)-1,2-Diphenylethene SCHEMBL27513215 0.84 HDAC1 (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
(Z)-1,2-Diphenylethene SCHEMBL980839 0.84 HDAC1 (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL653828 0.82 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265602-A2 LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS TECHNISCHE UNIVERSITÄT WIEN (AT) 2023-10-25 — — EP claimed
CN-116790183-A High-refraction anti-fog low-cost UV (ultraviolet) coating for helmet mask and preparation method thereof 江苏三木化工股份有限公司 2023-09-22 — — CN claimed
CN-114432291-A Application of isopentene flavonoid compound in preparation of medicine 苏州凯祥生物科技有限公司 2022-05-06 — — CN claimed
CN-110885336-B 17-hydroxy-jolkinolide B derivative, preparation method and application 大连医科大学 2022-02-01 — — CN claimed
US-20210369702-A1 METHODS FOR TREATING ANEMIA IN SUBJECTS HAVING KIDNEY FAILURE USING INHIBITORS OF HYPOXIA-INDUCIBLE FACTOR (HIF) HYDROXYLASE FIBROGEN, INC. (US) 2021-12-02 — — US claimed
US-20210072447-A1 POLARIZATION DIFFRACTION ELEMENT AND VECTOR BEAM MODE DETECTION SYSTEM USING THE SAME UNIVERSITY OF HYOGO (JP) 2021-03-11 — — US claimed
US-10927081-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-02-23 — — US claimed
US-10894774-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-19 — — US claimed
US-10882827-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-05 — — US claimed
US-10626090-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN INC. (US) 2020-04-21 — — US claimed
US-4451473-A 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1984-05-29 — — US claimed
US-4434179-A POLYPRENYL DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1984-02-28 — — US claimed
US-4268514-A ANALGESICS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 — — US claimed
US-4260551-A ALIPHATIC OR AROMATIC ESTERS, ANTIULCER AGENTS SANKYO COMPANY LIMITED (JP) 1981-04-07 — — US claimed
US-4192953-A TREATMENT OF PEPTIC ULCERS SANKYO COMPANY LIMITED (JP) 1980-03-11 — — US claimed
US-4161588-A Polymerizable esters CIBA-GEIGY CORPORATION (US) 1979-07-17 — — US claimed
US-4116241-A FOR CONTROLLED ORAL ADMINISTRATION OF DRUG ALZA CORPORATION (US) 1978-09-26 — — US claimed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 — — US claimed
US-4008213-A WATER INSOLUBLE UGINE KUHLMANN (FR) 1977-02-15 — — US claimed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369702-A1 METHODS FOR TREATING ANEMIA IN SUBJECTS HAVING KIDNEY FAILURE USING INHIBITORS OF HYPOXIA-INDUCIBLE FACTOR (HIF) HYDROXYLASE HIF1AN, HIF1A, EGLN2 MAPT 4792/4885HDAC3 1029/4885HDAC4 599/4885
US-10626090-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC MAPT 4798/4885HDAC3 954/4885HDAC4 1589/4885
US-10894774-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC MAPT 4637/4885HDAC3 833/4885HDAC4 1009/4885
US-10927081-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC MAPT 4637/4885HDAC3 833/4885HDAC4 1009/4885
US-10882827-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC MAPT 4742/4885HDAC3 812/4885HDAC4 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.