SCHEMBL4101366

SCHEMBL4101366

Fc1nc(F)c(F)c(Br)c1F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7176619 0.80 MEN1 (0.34) MEN1MAPTHTTKMT2A
SCHEMBL21974636 0.80 LMNA (0.32)
SCHEMBL12309889 0.80 LMNA (0.32)
SCHEMBL14986201 0.74
SCHEMBL12251088 0.74
SCHEMBL188694 0.72 MEN1 (0.41) MEN1MAPTHTTKMT2A
SCHEMBL2650044 0.71
SCHEMBL3834812 0.71
SCHEMBL164556 0.71
SCHEMBL443601 0.69 MEN1 (0.46) MEN1MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
US-12029116-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2024-07-02 US disclosed
CN-114933591-B Pyridine derivative and application thereof 北京鼎材科技有限公司 2024-06-04 CN disclosed
CN-110407810-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2023-11-24 CN disclosed
CN-114933591-A Pyridine derivatives and use thereof 北京鼎材科技有限公司 2022-08-23 CN disclosed
CN-110491999-B Modification method of electron transport layer for organic solar cell 太原理工大学 2022-04-12 CN disclosed
US-20210305517-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-09-30 US disclosed
WO-2021080508-A1 METHOD AND SYSTEM FOR SYNTHESISING COMPOUNDS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-04-29 WO disclosed
CN-110872298-A Condensed ring aryl compound, organic electronic device and application thereof 宁波卢米蓝新材料有限公司 2020-03-10 CN disclosed
US-5693646-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5693647-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5688808-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
US-5688810-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 EP disclosed
US-5674880-A ANTIINFLAMMATORY AGENT CELLTECH THERAPEUTICS LIMITED (GB) 1997-10-07 US disclosed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 WO disclosed
US-5491147-A PHOSPHODIESTERASE IV INHIBITORS CELLTECH, LIMITED (GB) 1996-02-13 US disclosed
EP-0618889-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION CELLTECH THERAPEUTICS LIMITED (GB) 1994-10-12 EP disclosed
WO-1994010118-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION CELLTECH LIMITED (GB) 1994-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029116-B2 Composition of matter for use in organic light-emitting diodes OPRD1, DRD1, DRD3 MEN1 3613/4885MAPT 600/4885HTT 3293/4885
US-20210305517-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES OPRD1, DRD1, DRD3 MEN1 3613/4885MAPT 600/4885HTT 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.