Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185832 | 0.91 | — | — | |
| SCHEMBL3172604 | 0.88 | — | — | |
| SCHEMBL5331269 | 0.88 | — | — | |
| SCHEMBL9746820 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1372205 | 0.88 | — | — | |
| SCHEMBL1533989 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL9196640 | 0.85 | HMGCR (0.48) | ACLYALDH1A1HMGCRCHRM1TBXA2R | |
| Acetic Acid SCHEMBL288009 | 0.82 | HMGCR (0.46) | ACLYALDH1A1HMGCRCHRM1TBXA2R | |
| Methylene Chloride SCHEMBL18039031 | 0.82 | ACLY (0.42) | ACLYALDH1A1HMGCRCHRM1TBXA2R | |
| Acetic Acid SCHEMBL29833661 | 0.80 | HMGCR (0.43) | ACLYALDH1A1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221543-A1 | NEW CORTICOSTEROIDS | NICOX S A. (FR) | 2009-09-03 | — | — | US | disclosed |
| US-20060052594-A1 | New corticosteroids | NICOX S.A. (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1470150-A2 | CORTICOSTEROIDS NITRATE DERIVATIVES | Nicox S.A. (FR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064443-A2 | NEW CORTICOSTEROIDS | NICOX S.A. (FR) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221543-A1 | NEW CORTICOSTEROIDS | CYP11B1, NR3C1, NR3C2 | ACLY 3540/4885ALDH1A1 1055/4885HMGCR 316/4885 |
| US-20060052594-A1 | New corticosteroids | CYP11B1, NR3C1, NR3C2 | ACLY 3540/4885ALDH1A1 1055/4885HMGCR 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.