SCHEMBL677362

SCHEMBL677362

COC(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)CC(=O)Oc3ccc(C(C)(C)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
GAA P10253 2/20 0.47
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 3/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410353 0.92 LMNA (0.48) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL18969717 0.92 LMNA (0.49) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL12722242 0.91 LMNA (0.50) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL14281976 0.87 LMNA (0.43) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL6934422 0.86 ELANE (0.46) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL15827154 0.84 LMNA (0.53) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL14191447 0.83 LMNA (0.48) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL11925425 0.82 KMT2A (0.41) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL14208313 0.81 LMNA (0.51) LMNAGAAALDH1A1MAPTHSD17B10
SCHEMBL3424216 0.81 MAPT (0.51) LMNAGAAKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639417-B2 Method for the manufacture of poly(aliphatic ester-carbonate) compositions and articles thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-02 US disclosed
US-20170218132-A1 METHOD OF MAKING PLASTIC ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2017-08-03 US disclosed
US-20170190907-A1 HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-06 US disclosed
US-20170158853-A1 HIGH FLOW, HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-08 US disclosed
US-20170101530-A1 THERMAL CONDUCTIVE COMPOSITIONS HAVING GOOD IMPACT PERFORMANCE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-04-13 US disclosed
US-9574083-B2 Synergistic effect of multiple mold release additives in polycarbonate based compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-21 US disclosed
US-9328238-B2 Wear resistant compositions with low particulate contamination and method of making those compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-05-03 US disclosed
US-9284449-B2 Reinforced thermoplastic compound with chemical resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-15 US disclosed
US-20150368458-A1 REINFORCED THERMOPLASTIC COMPOUND WITH CHEMICAL RESISTANCE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2015-12-24 US disclosed
US-20150353732-A1 IMPACT IMPROVED FILLED POLYCARBONATE OR POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-12-10 US disclosed
US-8440762-B2 Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-14 US disclosed
US-8404772-B2 Polymer compositions, method of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-03-26 US disclosed
US-20120184661-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-19 US disclosed
US-20120184662-A1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-19 US disclosed
US-8084134-B2 Transparent thermoplastic compositions having high flow and ductiliy, and articles prepared therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-27 US disclosed
US-8064140-B2 Transparent articles prepared from thermoplastic compositions having low birefringence SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-22 US disclosed
US-20110071261-A1 TRANSPARENT ARTICLES PREPARED FROM THERMOPLASTIC COMPOSITIONS HAVING LOW BIREFRINGENCE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-03-24 US disclosed
US-7848025-B2 Transparent articles prepared from thermoplastic compositions having high flow and ductility, and method of preparing articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-12-07 US disclosed
US-20100168370-A1 TRANSPARENT ARTICLES PREPARED FROM THERMOPLASTIC COMPOSITIONS HAVING HIGH FLOW AND DUCTILITY, AND METHOD OF PREPARING ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-07-01 US disclosed
US-20100129649-A1 TRANSPARENT THERMOPLASTIC COMPOSITIONS HAVING HIGH FLOW AND DUCTILIY, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS, IP B.V (NL) 2010-05-27 US disclosed