Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125608 | 0.86 | MEN1 (0.61) | CNR1MAPTGAAHTTLMNA | |
| SCHEMBL4116381 | 0.85 | MCHR1 (0.58) | CNR1MCHR1MAPTNPSR1GAA | |
| SCHEMBL4107284 | 0.85 | MCHR1 (0.59) | MCHR1MAPTNPSR1GAAKDM4E | |
| SCHEMBL4118097 | 0.84 | LMNA (0.51) | CNR1MCHR1MAPTNPSR1GAA | |
| SCHEMBL4120327 | 0.83 | LMNA (0.65) | MCHR1MAPTNPSR1GAATDP1 | |
| SCHEMBL4119645 | 0.82 | MCHR1 (0.60) | CNR1MCHR1MAPTGAAHTT | |
| SCHEMBL4114249 | 0.81 | MCHR1 (0.59) | CNR1MCHR1MAPTGAAKDM4E | |
| SCHEMBL11797984 | 0.79 | MCHR1 (0.61) | MCHR1MAPTNPSR1GAAKDM4E | |
| SCHEMBL4106239 | 0.78 | MCHR1 (0.52) | CNR1MCHR1HTTLMNASMN1; SMN2 | |
| SCHEMBL4118347 | 0.77 | LMNA (0.56) | MCHR1MAPTNPSR1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2009-05-07 | — | — | US | disclosed |
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | IL2, CASP2, MAVS | CNR1 3201/4885MCHR1 4128/4885MAPT 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.