Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107182 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL4112804 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL4112796 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15797772 | 0.78 | CA12 (0.51) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15797717 | 0.78 | CA12 (0.51) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL1532533 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15805563 | 0.77 | MAPT (0.56) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL1845901 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL1843245 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8342115 | 0.74 | CA12 (0.53) | MAPTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047223-A1 | Improvements in or Related to Organic Compoounds | GIVAUDAN SA (CH) | 2009-02-19 | — | — | US | claimed |
| US-20090047223-A1 | Improvements in or Related to Organic Compoounds | GIVAUDAN SA (CH) | 2009-02-19 | — | — | US | disclosed |
| EP-1966117-A1 | IMPROVEMENTS IN OR RELATED TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071085-A1 | IMPROVEMENTS IN OR RELATED TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047223-A1 | Improvements in or Related to Organic Compoounds | LPO, OTC, OAT | SMN1; SMN2 1471/4885LMNA 4030/4885MAPT 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.