Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.52 |
| ▸ | UBE2M | P61081 | 4/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106984 | 0.96 | EPHX2 (0.58) | CASREPHX2DCUN1D1UBE2MCCR3 | |
| SCHEMBL4118060 | 0.95 | EPHX2 (0.59) | CASREPHX2DCUN1D1UBE2MCCR3 | |
| SCHEMBL4111553 | 0.95 | CASR (0.53) | CASREPHX2DCUN1D1UBE2MCCR3 | |
| SCHEMBL4116411 | 0.93 | CNR1 (0.54) | CASREPHX2DCUN1D1UBE2MCCR3 | |
| SCHEMBL4115069 | 0.92 | ALOX15 (0.52) | CASREPHX2DCUN1D1UBE2MCCR3 | |
| SCHEMBL4124304 | 0.88 | MEN1 (0.58) | CASREPHX2CCR3HRH3KMT2A | |
| SCHEMBL4119717 | 0.87 | EPHX2 (0.57) | CASREPHX2CCR3HRH3KMT2A | |
| SCHEMBL4115134 | 0.87 | MEN1 (0.53) | CASRKMT2APOLBMEN1MCHR1 | |
| SCHEMBL4123912 | 0.87 | EPHX2 (0.61) | EPHX2CCR3HRH3KMT2APOLB | |
| SCHEMBL30041940 | 0.86 | EPHX2 (0.67) | EPHX2CCR3HRH3KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2009-05-07 | — | — | US | claimed |
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | claimed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | claimed |
| US-20090118330-A1 | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2009-05-07 | — | — | US | disclosed |
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | IL2, CASP2, MAVS | CASR 2199/4885EPHX2 1614/4885DCUN1D1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.