Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554162 | 0.83 | CYP2A6 (0.54) | CYP1A2CYP2A6IDO1PHOSPHO1PCSK9 | |
| SCHEMBL30071339 | 0.83 | CYP2A6 (0.54) | CYP1A2CYP2A6IDO1PHOSPHO1PCSK9 | |
| SCHEMBL30366437 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18530961 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6IDO1HSD17B1HSD17B2 | |
| SCHEMBL30366550 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6IDO1PCSK9HSD17B1 | |
| SCHEMBL30366566 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1780245 | 0.77 | CYP1A2 (0.58) | CYP1A2CYP2A6CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5748246 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6IDO1PCSK9HSD17B1 | |
| SCHEMBL9730016 | 0.77 | CYP2A6 (0.52) | CYP1A2CYP2A6MEN1ALDH1A1KMT2A | |
| SCHEMBL30366173 | 0.77 | CYP1A2 (0.52) | CYP1A2CYP2A6IDO1PCSK9HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| CN-101155817-A | Dihydroimidazothiazole derivatives | PROSIDION LTD (GB) | 2008-04-02 | — | — | CN | disclosed |
| WO-2007147775-A1 | PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-12-27 | — | — | WO | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | CYP1A2 137/4885CYP2A6 447/4885IDO1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.