SCHEMBL410871

SCHEMBL410871

C=CCCc1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
HTR2A P28223 1/20 0.50
PYCR1 P32322 1/20 0.47
GPR52 Q9Y2T5 1/20 0.43
TGM2 P21980 1/20 0.41
CYP2A6 P11509 1/20 0.38
IDO1 P14902 2/20 0.38
PDPK1 O15530 1/20 0.36
POLB P06746 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
LSS P48449 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7857937 0.88 TAAR1 (0.41) TAAR1HTR2APYCR1GPR52TGM2
SCHEMBL9004469 0.87 GFER (0.36)
SCHEMBL8062755 0.86 TAAR1 (0.46) TAAR1HTR2APYCR1GPR52TGM2
SCHEMBL6285109 0.85 GFER (0.41)
SCHEMBL8073311 0.85 TAAR1 (0.45) TAAR1HTR2APYCR1GPR52TGM2
SCHEMBL6141697 0.84 TAAR1 (0.37) TAAR1HTR2APYCR1GPR52TGM2
SCHEMBL7859007 0.84 TAAR1 (0.37) TAAR1HTR2APYCR1GPR52TGM2
SCHEMBL15065059 0.83 USP2 (0.44) TAAR1HTR2APYCR1GPR52
SCHEMBL8078219 0.83 USP2 (0.44) TAAR1HTR2APYCR1GPR52
SCHEMBL8072998 0.83 USP2 (0.44) TAAR1HTR2APYCR1GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372489-B Temperature-sensitive delayed water shutoff agent and preparation method and application thereof 山东诺尔生物科技有限公司 2021-10-29 CN claimed
CN-113372489-A Temperature-sensitive delayed water shutoff agent and preparation method and application thereof 山东诺尔生物科技有限公司 2021-09-10 CN claimed
EP-2173740-A1 HEME-OXYGENASE INHIBITORS AND USE OF THE SAME IN THE TREATMENT OF CANCER AND DISEASES OF THE CENTRAL NERVOUS SYSTEM Osta Biotechnologies (CA) 2010-04-14 EP claimed
WO-2008151437-A1 HEME-OXYGENASE INHIBITORS AND USE OF THE SAME IN THE TREATMENT OF CANCER AND DISEASES OF THE CENTRAL NERVOUS SYSTEM OSTA BIOTECHNOLOGIES (CA) 2008-12-18 WO claimed
EP-4504742-B1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2026-05-20 EP disclosed
US-20260116904-A1 SILOXANE FUNCTIONALIZED PLATINUM OXALATE COMPLEX DOW SILICONES CORP (US) 2026-04-30 US disclosed
EP-4709733-A1 SILOXANE FUNCTIONALIZED PLATINUM OXALATE COMPLEX Dow Silicones Corporation (US) 2026-03-18 EP disclosed
US-20250215160-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-03 US disclosed
US-20250206889-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-26 US disclosed
WO-2025064221-A1 PHOTOCURABLE ORGANOPOLYSILOXANE RESIN DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-27 WO disclosed
WO-2025064220-A1 PHOTOCURABLE ORGANOPOLYSILOXANE RESIN DOW GLOBAL TECHNOLOGIES LLC (US) 2025-03-27 WO disclosed
EP-4504741-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR Dow Global Technologies LLC (US) 2025-02-12 EP disclosed
EP-0466183-B1 Cyclosiloxanes with mesogenic side groups CONSORTIUM ELEKTROCHEM IND (DE) 1995-09-20 EP disclosed
EP-0637580-A1 Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-08 EP disclosed
EP-0424959-B1 Organosilylalkyl-aromatic compounds CONSORTIUM ELEKTROCHEM IND (DE) 1995-02-01 EP disclosed
US-5304667-A Cyclosiloxanes containing mesogenic side groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-04-19 US disclosed
US-5221759-A CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-06-22 US disclosed
US-5210247-A ORGANOSILYLALKYLAROMATIC COMPOUNDS CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-05-11 US disclosed
EP-0466183-A1 Cyclosiloxanes with mesogenic side groups Consortium für elektrochemische Industrie GmbH (DE) 1992-01-15 EP disclosed
EP-0424959-A2 Organosilylalkyl-aromatic compounds Consortium für elektrochemische Industrie GmbH (DE) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206889-A1 SILICONE-SOLUBLE ACYLPHOSPHINE OXIDE PHOTOINITIATOR MSR1, PIGS, F12 TAAR1 1032/4885HTR2A 3296/4885PYCR1 2293/4885
US-20250215160-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATOR ARSA, H1-3, MPST TAAR1 2133/4885HTR2A 3023/4885PYCR1 2427/4885
US-20260116904-A1 SILOXANE FUNCTIONALIZED PLATINUM OXALATE COMPLEX CCRL2, ORC3, OXGR1 TAAR1 1296/4885HTR2A 4020/4885PYCR1 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.