Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14320158 | 1.00 | MAPK1 (0.57) | MAPK1CYP2C9LMNACHRM4CHRM2 | |
| SCHEMBL22311884 | 0.96 | — | — | |
| SCHEMBL278483 | 0.96 | MAPK1 (0.55) | MAPK1CYP2C9LMNACHRM4CHRM2 | |
| SCHEMBL44881 | 0.96 | — | — | |
| SCHEMBL12955575 | 0.96 | — | — | |
| SCHEMBL14434380 | 0.96 | — | — | |
| SCHEMBL44882 | 0.96 | — | — | |
| SCHEMBL24901096 | 0.93 | MAPK1 (0.52) | MAPK1CYP2C9LMNACHRM4CHRM2 | |
| Hydrochloric Acid SCHEMBL16245107 | 0.93 | MAPK1 (0.52) | MAPK1CYP2C9LMNACHRM4CHRM2 | |
| SCHEMBL22421153 | 0.93 | MAPK1 (0.52) | MAPK1CYP2C9LMNACHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286163-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | Johnson Matthey Public Limited Company (GB) | 2018-02-28 | — | — | EP | claimed |
| WO-2016172128-A1 | METHOD FOR PREPARING STRUCTURED DIRECTING AGENT | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-10-27 | — | — | WO | claimed |
| US-9371347-B2 | dppf-like compounds and method of manufacture and use | BROWN UNIVERSITY (US) | 2016-06-21 | — | — | US | claimed |
| US-20160002274-A1 | dppf-LIKE COMPOUNDS AND METHOD FO MANUFACTURE AND USE | NATIONAL SCIENCE FOUNDATION | 2016-01-07 | — | — | US | claimed |
| US-20150158020-A1 | SYNTHESIS OF ZEOLITES USING AN ORGANOAMMONIUM COMPOUND | UOP LLC | 2015-06-11 | — | — | US | claimed |
| WO-2014130410-A1 | DPPF-LIKE COMPOUNDS AND METHODS | BROWN UNIVERSITY (US) | 2014-08-28 | — | — | WO | claimed |
| US-8124600-B2 | 5-HT3 receptor modulators, methods of making, and use thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-02-28 | — | — | US | claimed |
| EP-2310019-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2011-04-20 | — | — | EP | claimed |
| WO-2009155054-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-12-23 | — | — | WO | claimed |
| US-20090298809-A1 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-12-03 | — | — | US | claimed |
| US-12480131-B2 | Tropane alkaloid (TA) producing non-plant host cells, and methods of making and using the same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-11-25 | — | — | US | disclosed |
| US-12391848-B2 | Polishing composition, method for producing polishing composition, polishing method, and method for producing semiconductor substrate | FUJIMI INCORPORATED (JP) | 2025-08-19 | — | — | US | disclosed |
| CN-113784758-B | Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same | 小利兰·斯坦福大学托管委员会 | 2025-03-07 | — | — | CN | disclosed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | disclosed |
| CN-113388328-B | Polishing composition, method for producing polishing composition, polishing method, and method for producing semiconductor substrate | 福吉米株式会社 | 2024-10-25 | — | — | CN | disclosed |
| EP-0618880-A1 | A PROCESS FOR PREPARING MOLECULAR SIEVES USING 9-AZABICYCLO[3.3.1]NONANE TEMPLATES | CHEVRON RESEARCH AND TECHNOLOGY COMPANY, (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008900-A1 | A PROCESS FOR PREPARING MOLECULAR SIEVES USING 9-AZABICYCLO[3.3.1]NONANE TEMPLATES | CHEVRON RESEARCH AND TECHNOLOGY COMPANY, A DIVISION OF CHEVRON U.S.A. INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5273736-A | Process for preparing molecular sieves using 9-azabicyclo [3.3.1] nonane templates | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5202333-A | Tricyclic 5-HT3 receptor antagonists | SYNTEX (U.S.A.) INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-4370323-A | 2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298809-A1 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | HTR3A, HTR5A, HTR3B | MAPK1 3092/4885CYP2C9 472/4885LMNA 4803/4885 |
| US-20160002274-A1 | dppf-LIKE COMPOUNDS AND METHOD FO MANUFACTURE AND USE | DBF4, CD22, CD2BP2 | MAPK1 3874/4885CYP2C9 1054/4885LMNA 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.