Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 11/20 | 0.39 |
| ▸ | F3 | P13726 | 11/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.35 |
| ▸ | F10 | P00742 | 6/20 | 0.35 |
| ▸ | F11 | P03951 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912061 | 0.88 | NR1H2 (0.41) | F7F3CA1CA2CA4 | |
| SCHEMBL3077286 | 0.88 | NR1H2 (0.41) | F7F3CA1CA2CA4 | |
| SCHEMBL4338373 | 0.88 | NR1H2 (0.41) | F7F3CA1CA2CA4 | |
| SCHEMBL3083078 | 0.88 | NR1H2 (0.41) | F7F3CA1CA2CA4 | |
| SCHEMBL2913738 | 0.88 | NR1H2 (0.41) | F7F3CA1CA2CA4 | |
| SCHEMBL5531271 | 0.85 | SLC6A4 (0.38) | F7F3CA1CA2CA4 | |
| SCHEMBL3079269 | 0.78 | SHMT2 (0.38) | F7F3HSD17B10 | |
| SCHEMBL2916946 | 0.76 | F7 (0.45) | F7F3F2F10F11 | |
| SCHEMBL3091021 | 0.76 | SHMT2 (0.37) | TSHR | |
| SCHEMBL13613432 | 0.76 | SLC6A3 (0.35) | F7F3F2F10F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061756-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENILACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2007146719-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENYLACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |