Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908616 | 0.87 | NR1H2 (0.39) | KMT2A | |
| SCHEMBL2908617 | 0.87 | NR1H2 (0.39) | KMT2A | |
| SCHEMBL4110657 | 0.85 | F7 (0.39) | SLC6A4SLC6A2SLC6A3HSD17B10CYP3A4 | |
| SCHEMBL5508811 | 0.79 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3HSD17B10ALDH1A1 | |
| SCHEMBL4477955 | 0.75 | ACHE (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4483774 | 0.75 | ACHE (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL2916156 | 0.74 | RIPK1 (0.45) | LMNAF7F3RIPK1 | |
| SCHEMBL4102794 | 0.74 | MEN1 (0.42) | HSD17B10ALDH1A1MAPTNPSR1TSHR | |
| SCHEMBL3077286 | 0.74 | NR1H2 (0.41) | ALDH1A1MAPTMAPK1KMT2ACA1 | |
| SCHEMBL2913738 | 0.74 | NR1H2 (0.41) | ALDH1A1MAPTMAPK1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856096-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | Bristol-Myers Squibb Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006076246-A2 | PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |