SCHEMBL411137

SCHEMBL411137

CC1(C)OB(c2ccc(N3C[C@H](CO)OC3=O)cc2F)OC1(C)C

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 7/20 0.56
MAOB P27338 6/20 0.52
MAOA P21397 5/20 0.52
CYP2C19 P33261 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.44
LMNA P02545 1/20 0.43
PTGS1 P23219 1/20 0.43
SDHA P31040 1/20 0.43
F10 P00742 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14838111 1.00 CALML3 (0.56) CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL13484703 0.90 F10 (0.46) CALML3MAOBMAOALMNAPTGS1
SCHEMBL10196142 0.90 CALML3 (0.44) CALML3MAOBMAOALMNAPTGS1
SCHEMBL15458115 0.87 CALML3 (0.42) CALML3MAOBMAOALMNAPTGS1
SCHEMBL24142630 0.87 CALML3 (0.42) CALML3MAOBMAOALMNAPTGS1
SCHEMBL14838114 0.87 CALML3 (0.41) CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL17801942 0.87 MAOA (0.45) CALML3MAOBMAOALMNAPTGS1
SCHEMBL1031591 0.86 MAOA (0.62) CALML3MAOBMAOALMNAPTGS1
SCHEMBL17801943 0.86 MAOA (0.45) CALML3MAOBMAOALMNAPTGS1
SCHEMBL1031592 0.86 MAOA (0.62) CALML3MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348447-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-11-02 US disclosed
US-20230219941-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-07-13 US disclosed
US-20230219941-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-07-13 US disclosed
WO-2023122759-A2 OXAZOLIDINONE LIPOSOME COMPOSITIONS AKAGERA MEDICINES, INC. (US) 2023-06-29 WO disclosed
US-20230126415-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-04-27 US disclosed
US-20230126415-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-04-27 US disclosed
US-11566023-B2 Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof AKAGERA MEDICINES, INC. (US) 2023-01-31 US disclosed
US-20210403463-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. 2021-12-30 US disclosed
CN-108368139-B Substituted oxazolidinone compounds and uses thereof 深圳市塔吉瑞生物医药有限公司 2020-12-18 CN disclosed
US-9487545-B2 Fused ring-containing oxazolidinones antibiotics Xuanzhu Pharma Co., Ltd. (CN) 2016-11-08 US disclosed
EP-2762480-A1 OXAZOLIDINONE ANTIBIOTICS CONTAINING FUSED RING Xuanzhu Pharma Co., Ltd. (CN) 2014-08-06 EP disclosed
US-20140179691-A1 NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME LEGOCHEM BIOSCIENCES, INC. (KR) 2014-06-26 US disclosed
US-20140179691-A1 NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME LEGOCHEM BIOSCIENCES, INC. (KR) 2014-06-26 US disclosed
EP-2692727-A2 NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME LegoChem Biosciences, Inc. (KR) 2014-02-05 EP disclosed
WO-2013044845-A1 BIARYL HETEROCYCLE SUBSTITUTED OXAZOLIDINON ANTIBACTERIAL DRUG 山东轩竹医药科技有限公司 (CN) 2013-04-04 WO disclosed
WO-2013044865-A1 OXAZOLIDINONE ANTIBIOTICS CONTAINING FUSED RING 山东轩竹医药科技有限公司 (CN) 2013-04-04 WO disclosed
WO-2012134188-A2 NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME 주식회사 레고켐 바이오사이언스 (KR) 2012-10-04 WO disclosed
US-20120065170-A1 Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections MICURX PHARMACEUTICALS, INC. (KY) 2012-03-15 US disclosed
US-20120065170-A1 Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections MICURX PHARMACEUTICALS, INC. (KY) 2012-03-15 US disclosed
WO-2012033952-A1 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS, INC. (KY) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403463-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CALML3 2409/4885MAOB 1216/4885MAOA 1751/4885
US-20140179691-A1 NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME OXA1L, PAM, ABCC1 CALML3 4088/4885MAOB 2328/4885MAOA 3122/4885
US-20230126415-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CALML3 2409/4885MAOB 1216/4885MAOA 1751/4885
US-20230219941-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF OXA1L, THPO, TBCD CALML3 2394/4885MAOB 1447/4885MAOA 1955/4885
US-20120065170-A1 Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections NISCH, SI, VIP CALML3 1652/4885MAOB 427/4885MAOA 853/4885
US-11566023-B2 Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof OXA1L, THPO, TBCD CALML3 2409/4885MAOB 1216/4885MAOA 1751/4885
US-20230348447-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CALML3 2409/4885MAOB 1216/4885MAOA 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.