SCHEMBL411193

SCHEMBL411193

CCC(=O)Nc1ccc2ncsc2c1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.57
NPC1 O15118 6/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NTRK1 P04629 4/20 0.52
NTRK2 Q16620 4/20 0.52
MAPT P10636 4/20 0.52
TP53 P04637 1/20 0.52
POLB P06746 1/20 0.51
ROCK1 Q13464 1/20 0.50
RXFP1 Q9HBX9 1/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
GFER P55789 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6653400 0.88 HSD11B1 (0.58) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL14697393 0.85 NPC1 (0.54) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL12354787 0.85 NTRK1 (0.55) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL8863163 0.83 LDHA (0.57) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL22341606 0.81 NPC1 (0.58) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL13491669 0.81 ROCK1 (0.60) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL3780938 0.81 NPC1 (0.56) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL13491608 0.81 ROCK1 (0.66) RAB9ANPC1MEN1KMT2ASMN1; SMN2
SCHEMBL25854530 0.80 NPC1 (0.55) RAB9ANPC1MEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL5548005 0.79 NPC1 (0.57) RAB9ANPC1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408769-A1 PYRIMIDINE DERIVATIVES USED AS ITK INHIBITORS Glaxo Group Limited (GB) 2012-01-25 EP disclosed
WO-2010106016-A1 PYRIMIDINE DERIVATIVES USED AS ITK INHIBITORS GLAXO GROUP LIMITED (GB) 2010-09-23 WO disclosed
EP-1211555-B1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJIFILM CORP (JP) 2008-12-31 EP disclosed
US-6875562-B2 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 2005-04-05 US disclosed
US-20030215760-A1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. 2003-11-20 US disclosed
US-6537742-B2 Photosensitivity; light absorption strength; latent imaging FUJI PHOTO FILM CO., LTD. (JP) 2003-03-25 US disclosed
EP-0838719-B1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 2003-02-12 EP disclosed
US-20020150848-A1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. 2002-10-17 US disclosed
EP-1211555-A2 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 2002-06-05 EP disclosed
US-6387610-B1 SILVER HALIDE EMULSION SPECTRA SENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 2002-05-14 US disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0618492-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-05 EP disclosed
EP-0608777-A1 Processing of lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-08-03 EP disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed
US-5260183-A Cyanine dye, thiocyanate, triazolopyrimidine spectral sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed
US-5035984-A Computer output images, nucleating agent FUJI PHOTO FILM CO., LTD. (JP) 1991-07-30 US disclosed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
US-4917997-A MIXED WITH ASCORBIC ACID COMPONENT, SENSITIZING DYE, BISAMINOSTILBENE WITH PYRIMIDINE SUBSTITUTION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0331185-A2 Silver halide photographic element for forming direct positive images and a method for forming said images FUJI PHOTO FILM CO., LTD. (JP) 1989-09-06 EP disclosed