SCHEMBL6653400

SCHEMBL6653400

CCC(=O)Nc1ccc2scnc2c1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.58
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
AURKA O14965 1/20 0.50
HIF1A Q16665 1/20 0.50
CYP3A4 P08684 1/20 0.49
RAB9A P51151 7/20 0.48
NPC1 O15118 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 2/20 0.46
TP53 P04637 1/20 0.46
RORC P51449 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411193 0.88 RAB9A (0.57) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL11770138 0.85 HSD11B1 (0.58) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL2335759 0.83 HSD11B1 (0.62) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL22341666 0.81 HSD11B1 (0.63) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL9508191 0.79 HSD11B1 (0.58) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL11507433 0.77 ESR1 (0.52) HSD11B1RAB9ANPC1SMN1; SMN2MEN1
SCHEMBL13076421 0.77 HSD11B1 (0.55) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL14035669 0.76 TRPM5 (0.57) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL18180168 0.76 HSD11B1 (0.54) HSD11B1KEAP1NFE2L2AURKAHIF1A
SCHEMBL28167267 0.75 MAPT (0.61) CYP3A4RAB9ANPC1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531759-B1 Process for preparing a photographic silver halide photosensitive material FUJI PHOTO FILM CO LTD (JP) 2004-06-02 EP disclosed
US-6548239-B2 Wherein photosensitive silver halide is spectrally sensitized with a dye to extend wavelength; suitable for infrared semiconductor lasers FUJI PHOTO FILM CO., LTD. (JP) 2003-04-15 US disclosed
US-20020081542-A1 Wherein photosensitive silver halide is spectrally sensitized with a dye to extend wavelength; suitable for infrared semiconductor lasers FUJIFILM CORPORATION (JP) 2002-06-27 US disclosed
EP-0531759-A2 Photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-03-17 EP disclosed