Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.41 |
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2675423 | 0.88 | NOS1 (0.47) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4106184 | 0.87 | NOS1 (0.48) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4107556 | 0.86 | NOS1 (0.49) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4114999 | 0.85 | NOS3 (0.48) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4106181 | 0.85 | NOS3 (0.49) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4104985 | 0.82 | NOS1 (0.45) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4113853 | 0.81 | NOS3 (0.62) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4106267 | 0.81 | NOS3 (0.45) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL4106186 | 0.81 | TP53 (0.42) | NOS3NOS1TP53LMNAPOLB | |
| SCHEMBL2675060 | 0.80 | NOS3 (0.62) | NOS3NOS1TP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173813-B2 | selectively inhibit neuronal nitric oxide synthase in combination with other pharmaceutically active agents; antidepressants | NEURAXON, INC. (CA) | 2012-05-08 | — | — | US | disclosed |
| US-20080234237-A1 | QUINOLONE AND TETRAHYDROQUINOLONE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234237-A1 | QUINOLONE AND TETRAHYDROQUINOLONE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NOS1, NOS2, NOS3 | NOS3 3/4885NOS1 1/4885TP53 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.