SCHEMBL411275

SCHEMBL411275

Cc1cc(-c2ccccc2)cc(C)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.70
CA2 P00918 1/20 0.70
CRHBP P24387 2/20 0.54
CRHR2 Q13324 2/20 0.54
ALOX5 P09917 2/20 0.54
TTR P02766 1/20 0.54
PTGS1 P23219 1/20 0.54
PTGS2 P35354 1/20 0.54
ADORA2A P29274 1/20 0.51
ADORA1 P30542 1/20 0.51
ESR2 Q92731 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ACHE P22303 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
DUSP3 P51452 1/20 0.46
MMP3 P08254 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL7039341 0.88 CA1 (0.67) CA1CA2CRHBPCRHR2ALOX5
SCHEMBL17060490 0.87 CA1 (0.82) CA1CA2ALOX5TTRPTGS1
SCHEMBL16581476 0.85 CA1 (0.70) CA1CA2ALOX5TTRPTGS1
SCHEMBL31028131 0.84 CA1 (0.54) CA1CA2CRHBPCRHR2ALOX5
SCHEMBL172874 0.84 CA1 (0.54) CA1CA2CRHBPCRHR2ALOX5
SCHEMBL22804025 0.84 CA1 (1.00) CA1CA2ALOX5TTRPTGS1
SCHEMBL220910 0.84 CA1 (1.00) CA1CA2ALOX5TTRPTGS1
SCHEMBL11318455 0.83 CA1 (0.48) CA1CA2CRHBPCRHR2ALOX5
Methane SCHEMBL27455003 0.82 CA1 (0.52) CA1CA2ALOX5TTRPTGS1
Biphenyl SCHEMBL28178319 0.82 ALDH1A1 (0.74) CA1CA2CRHBPCRHR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101305030-B Polyfunctional poly(arylene ether) method GEN ELECTRIC 2011-07-13 CN claimed
CN-101305030-A Polyfunctional poly(arylene ether) method GEN ELECTRIC (US) 2008-11-12 CN claimed
CN-100383173-C Method of preparing transparent silicone-containing copolycarbonates GEN ELECTRIC (US) 2008-04-23 CN claimed
CN-1263784-C Bisphenol type flame-retardant polycarbonate solution method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2006-07-12 CN claimed
CN-1688630-A Method of preparing transparent silicone-containing copolycarbonates GEN ELECTRIC (US) 2005-10-26 CN claimed
EP-1543061-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP claimed
CN-1569920-A Bisphenol type flame-retardant polycarbonate solution method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2005-01-26 CN claimed
CN-1569919-A Bisphenol type flame-retardant polycarbonate interface method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2005-01-26 CN claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
WO-2004016674-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-20240425448-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-12-26 US disclosed
EP-4431491-A1 CARBONYL COMPOUND, METHOD FOR PRODUCING CARBONYL COMPOUND, METHOD FOR PRODUCING ISOCYANATE COMPOUND, AND ISOCYANATE COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2024-09-18 EP disclosed
EP-4431490-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2024-09-18 EP disclosed
WO-2001019822-A1 ANTIVIRAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2001-03-22 WO disclosed
EP-0468162-A1 Modified polyphenylene ether based thermoplastic moulding compositions HÜLS AKTIENGESELLSCHAFT (DE) 1992-01-29 EP disclosed
EP-0448748-A1 Method for preparing aromatic sulfones SANKO CHEMICAL COMPANY LTD. (JP) 1991-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425448-A1 METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION IDH3A, CA7, C9 CA1 16/4885CA2 30/4885CRHBP 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.