Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028131 | 1.00 | CA1 (0.54) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL510022 | 0.91 | ESR2 (0.55) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL14344874 | 0.86 | CYP1A2 (0.62) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL8986922 | 0.85 | ESR2 (0.52) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL2861284 | 0.85 | ESR2 (0.62) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL411275 | 0.84 | CA1 (0.70) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL9469340 | 0.84 | PTPN1 (0.63) | ESR2PTPN1BACE1PDE4BALOX5 | |
| SCHEMBL27734232 | 0.83 | ESR2 (0.53) | CA1CA2ESR2PTPN1BACE1 | |
| SCHEMBL6572603 | 0.82 | ESR2 (0.48) | ESR2PTPN1BACE1PDE4BALOX5 | |
| SCHEMBL13997558 | 0.82 | AKR1C3 (0.59) | ESR2PTPN1BACE1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096566-B2 | Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| EP-1521125-B1 | Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120029164-A1 | ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| US-7556902-B2 | Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof | RICOH COMPANY, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7556902-B2 | Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof | RICOH COMPANY, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-7452640-B2 | Electrophotographic photoconductor for liquid development, image forming apparatus having the same, and image forming method | RICOH COMPANY, LTD. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7452640-B2 | Electrophotographic photoconductor for liquid development, image forming apparatus having the same, and image forming method | RICOH COMPANY, LTD. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7175958-B2 | Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same | RICOH COMPANY, LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-7175958-B2 | Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same | RICOH COMPANY, LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029164-A1 | ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME | ALK, ALKBH3, IGLV6-57 | CA1 196/4885CA2 688/4885ESR2 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.