Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113384 | 1.00 | KMT2A (0.43) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL335366 | 0.77 | LMNA (0.41) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL335365 | 0.77 | LMNA (0.41) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10891483 | 0.77 | ALDH1A1 (0.53) | KMT2AMEN1MAPTALDH1A1NPSR1 | |
| SCHEMBL4100731 | 0.76 | PLG (0.54) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL4086777 | 0.75 | MAPT (0.58) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL699996 | 0.75 | MAPT (0.58) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL8210875 | 0.72 | NAMPT (0.54) | KMT2AMEN1MAPTNPSR1NPC1 | |
| SCHEMBL17094907 | 0.71 | POLB (0.58) | KMT2AMEN1MAPTNPC1POLB | |
| SCHEMBL356816 | 0.70 | MEN1 (0.51) | KMT2AMEN1MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263621-B2 | Tartrate derivatives for use as coagulation factor IXa inhibitors | SANOFI (FR) | 2012-09-11 | — | — | US | disclosed |
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | SANOFI-AVENTIS (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233961-A1 | TARTRATE DERIVATIVES FOR USE AS COAGULATION FACTOR IXA INHIBITORS | TFPI, TFPI2, F9 | KMT2A 3068/4885MEN1 3850/4885MAPT 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.