3,4,5-Trihydroxy-Transstilbene

3,4,5-Trihydroxy-Transstilbene

SCHEMBL41159

Oc1cc(/C=C/c2ccccc2)cc(O)c1O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.63
PTGS1 P23219 2/20 0.63
TTR P02766 1/20 0.63
ALOX5 P09917 1/20 0.63
AHR P35869 1/20 0.62
TRPA1 O75762 1/20 0.56
TUBB1 Q9H4B7 1/20 0.53
PTPN1 P18031 3/20 0.50
CYP3A4 P08684 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TRPV1 Q8NER1 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4,5-Trihydroxy-Transstilbene SCHEMBL41160 1.00 PTGS2 (0.63) PTGS2PTGS1TTRALOX5AHR
SCHEMBL15542754 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
SCHEMBL15542753 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
(Z)-1,2-Diphenylethene SCHEMBL27882852 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
SCHEMBL4608754 0.84 PTGS2 (0.54) PTGS2PTGS1TTRALOX5TUBB1
SCHEMBL4608757 0.84 PTGS2 (0.54) PTGS2PTGS1TTRALOX5TUBB1
SCHEMBL3645729 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL3645732 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL2718303 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL10597010 0.82 PTPN1 (0.71) PTGS2PTGS1TTRALOX5AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014039011-A1 METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-03-13 WO claimed
US-20060286046-A1 Skin care compositions HABER C ANDREW 2006-12-21 US claimed
WO-2006072175-A1 SKIN CARE COMPOSITIONS HABER DERMACEUTICS INC. (CA) 2006-07-13 WO claimed
US-20050020511-A1 Use of stilbene compounds in preparing medicaments for treating or preventing diabetes and diseases associated with retrovirus BEIJING LUYIN LIHUA PHARMACEUTICAL SCIENCE AND TECHNOLOGY DEVELOPMENT COMPANY LTD (CN) 2005-01-27 US claimed
EP-1421933-A1 USE OF STILBENE COMPOUNDS IN PREPARING MEDICAMENTS FOR TREATING OR PREVENTING DIABETES AND DISEASES ASSOCIATED WITH RETROVIRUS Institute of Radiation Medicine, Academy of Military Medical Sciences Pla (CN) 2004-05-26 EP claimed
EP-1280556-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-02-05 EP claimed
WO-2001085142-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2001-11-15 WO claimed
CN-122012264-A Yarrowia lipolytica BS-3 and application thereof in resveratrol production 杭州精构生物科技有限责任公司 2026-05-12 CN disclosed
US-12515955-B2 Carbon material, use thereof in batteries, method for producing said material and electrode comprising same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2026-01-06 US disclosed
WO-2025224591-A1 ORAL PRODUCT WITH FLAVOR EMULSION Nicoventures Trading Limited (GB) 2025-10-30 WO disclosed
EP-3943071-B1 COMPOSITION COMPRISING NATURAL LIPOPHILIC COMPOUNDS, USE OF THE COMPOSITION AND METHOD FOR PREPARING THE COMPOSITION KHINIKADZE ZURAB DURMISCHCHANOWITCH (RU) 2025-06-18 EP disclosed
CN-119837847-A Application of resveratrol in preparation of products for preventing and/or treating recurrent abortion caused by unknown reasons 安徽医科大学第一附属医院 2025-04-18 CN disclosed
CN-119033705-B Preparation method and application of GelMA Cryogel microsphere carrying resveratrol nanocrystal 吉林大学 2025-02-11 CN disclosed
EP-1280556-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-02-05 EP disclosed
CN-1385535-A Method for raising Resveratrol content in Chinese herb-giant knotweed rhizome SHENZHEN QINGHUA MORDERN CHINE (CN) 2002-12-18 CN disclosed
WO-2001091695-A2 THE USE OF RESVERATROL AS SUNSCREEN D.B.P. DI ROSSI VALENTINA E C. S.N.C. (IT) 2001-12-06 WO disclosed
WO-2001091714-A1 USE OF STILBENE DERIVATIVES FOR DANDRUFF TREATMENT D.B.P. DI ROSSI VALENTINA E C. S.N.C. (US) 2001-12-06 WO disclosed
WO-2001085142-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2001-11-15 WO disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020511-A1 Use of stilbene compounds in preparing medicaments for treating or preventing diabetes and diseases associated with retrovirus POT1, SLC5A1, VHL PTGS2 2391/4885PTGS1 607/4885TTR 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.