3,4,5-Trihydroxy-Transstilbene

3,4,5-Trihydroxy-Transstilbene

SCHEMBL41160

Oc1cc(C=Cc2ccccc2)cc(O)c1O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.63
PTGS1 P23219 2/20 0.63
TTR P02766 1/20 0.63
ALOX5 P09917 1/20 0.63
AHR P35869 1/20 0.62
TRPA1 O75762 1/20 0.56
TUBB1 Q9H4B7 1/20 0.53
PTPN1 P18031 3/20 0.50
CYP3A4 P08684 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TRPV1 Q8NER1 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4,5-Trihydroxy-Transstilbene SCHEMBL41159 1.00 PTGS2 (0.63) PTGS2PTGS1TTRALOX5AHR
SCHEMBL15542754 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
SCHEMBL15542753 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
(Z)-1,2-Diphenylethene SCHEMBL27882852 0.87 PTGS2 (0.55) PTGS2PTGS1TTRALOX5AHR
SCHEMBL4608754 0.84 PTGS2 (0.54) PTGS2PTGS1TTRALOX5TUBB1
SCHEMBL4608757 0.84 PTGS2 (0.54) PTGS2PTGS1TTRALOX5TUBB1
SCHEMBL3645729 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL3645732 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL2718303 0.82 TUBB1 (0.70) PTGS2PTGS1TTRALOX5AHR
SCHEMBL10597010 0.82 PTPN1 (0.71) PTGS2PTGS1TTRALOX5AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110577464-A Preparation method of resveratrol 山东博奥克生物科技有限公司 2019-12-17 CN claimed
WO-2014039011-A1 METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-03-13 WO claimed
US-20060286046-A1 Skin care compositions HABER C ANDREW 2006-12-21 US claimed
WO-2006072175-A1 SKIN CARE COMPOSITIONS HABER DERMACEUTICS INC. (CA) 2006-07-13 WO claimed
US-20050020511-A1 Use of stilbene compounds in preparing medicaments for treating or preventing diabetes and diseases associated with retrovirus BEIJING LUYIN LIHUA PHARMACEUTICAL SCIENCE AND TECHNOLOGY DEVELOPMENT COMPANY LTD (CN) 2005-01-27 US claimed
EP-1421933-A1 USE OF STILBENE COMPOUNDS IN PREPARING MEDICAMENTS FOR TREATING OR PREVENTING DIABETES AND DISEASES ASSOCIATED WITH RETROVIRUS Institute of Radiation Medicine, Academy of Military Medical Sciences Pla (CN) 2004-05-26 EP claimed
EP-1280556-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-02-05 EP claimed
WO-2001085142-A1 COMPOSITIONS AND METHODS FOR PROTECTING CELLS DURING CANCER CHEMOTHERAPY AND RADIOTHERAPY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2001-11-15 WO claimed
US-12515955-B2 Carbon material, use thereof in batteries, method for producing said material and electrode comprising same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2026-01-06 US disclosed
EP-3943071-B1 COMPOSITION COMPRISING NATURAL LIPOPHILIC COMPOUNDS, USE OF THE COMPOSITION AND METHOD FOR PREPARING THE COMPOSITION KHINIKADZE ZURAB DURMISCHCHANOWITCH (RU) 2025-06-18 EP disclosed
CN-119464097-A Kluyveromyces marxianus INM3116 and preparation and application thereof 浙江一鸣食品股份有限公司 2025-02-18 CN disclosed
US-20250018044-A1 Methods of Making and Using Polyphenols Complexed With a Protein, Peptide, Amino Acid, Polysaccharide, Disaccharide, or Monosaccharide CHANCEY JOHN ROBERT (US) 2025-01-16 US disclosed
US-20240400983-A1 CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME Sumitomo Pharma Co., Ltd. (JP) 2024-12-05 US disclosed
US-20240392241-A1 METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-11-28 US disclosed
WO-2001043705-A2 COMPOSITIONS CONTAINING A RETINOID AND A STILBENE FOR SKIN CARE JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2001-06-21 WO disclosed
WO-2001021165-A1 RESVERATROL ANALOGS FOR PREVENTION OF DISEASE RUTGERS, THE STATE UNIVERSITY (US) 2001-03-29 WO disclosed
EP-1065946-A1 NATURAL SUBSTANCE BASED AGENT Stückler, Franz (AT) 2001-01-10 EP disclosed
WO-1999048386-A1 NATURAL SUBSTANCE BASED AGENT STUECKLER FRANZ (AT) 1999-09-30 WO disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020511-A1 Use of stilbene compounds in preparing medicaments for treating or preventing diabetes and diseases associated with retrovirus POT1, SLC5A1, VHL PTGS2 2391/4885PTGS1 607/4885TTR 671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.