Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117057 | 0.80 | GRIN2D (0.36) | DRD2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4390219 | 0.78 | DRD2 (0.48) | PRCPDRD2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16264959 | 0.74 | PTGS1 (0.36) | DRD2KDM1ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13189225 | 0.74 | DRD2 (0.35) | GAADRD2TSHRKDM4EALDH1A1 | |
| SCHEMBL4120535 | 0.72 | PRCP (0.50) | PRCPGAAGID4KDM1ARECQL | |
| SCHEMBL6986104 | 0.72 | PRCP (0.52) | PRCPGAAGID4RECQLTSHR | |
| SCHEMBL20563974 | 0.71 | MAPT (0.37) | GAADRD2TSHRKDM4EALDH1A1 | |
| SCHEMBL635407 | 0.70 | MAPT (0.49) | DRD2TSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29560409 | 0.70 | MAPT (0.49) | DRD2TSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7709361 | 0.69 | MAPT (0.37) | GAATSHRKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183378-B2 | Ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-05-22 | — | — | US | disclosed |
| US-8183378-B2 | Ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-05-22 | — | — | US | disclosed |
| US-20090247757-A1 | LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | CHAO-JUN LI (CA) | 2009-10-01 | — | — | US | disclosed |
| US-20090247757-A1 | LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | CHAO-JUN LI (CA) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247757-A1 | LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS | OGFR, OR10J3, OPRL1 | PRCP 3913/4885GAA 4883/4885DRD2 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.