Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452115 | 0.92 | DPP4 (0.42) | DPP4DPP9DPP8MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL4104910 | 0.84 | DPP4 (0.60) | DPP4DPP9DPP8 | |
| SCHEMBL5454058 | 0.83 | DPP4 (0.42) | DPP4DPP9DPP8 | |
| SCHEMBL4117655 | 0.79 | DPP4 (0.41) | DPP4DPP9DPP8 | |
| SCHEMBL4112465 | 0.78 | DPP4 (0.68) | DPP4DPP9DPP8KMT2A | |
| SCHEMBL5240240 | 0.76 | DPP4 (0.48) | DPP4DPP9DPP8MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL5451866 | 0.76 | DPP4 (0.62) | DPP4DPP9DPP8 | |
| SCHEMBL5452120 | 0.74 | DPP4 (0.39) | DPP4DPP9DPP8 | |
| SCHEMBL5447776 | 0.74 | DPP4 (0.46) | DPP4DPP9DPP8TDP1 | |
| SCHEMBL4117782 | 0.73 | DPP4 (0.49) | DPP4DPP9DPP8MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088419-A1 | PYRIDYL ACETIC ACID COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088419-A1 | PYRIDYL ACETIC ACID COMPOUNDS | DPP4, GPR119, DPP3 | DPP4 1/4885DPP9 11/4885DPP8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.