Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefoxitin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.98 |
| ▸ | PPARG | P37231 | 1/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | MEN1 | O00255 | 3/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.84 |
| ▸ | POLB | P06746 | 2/20 | 0.84 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefoxitin SCHEMBL28808173 | 1.00 | NR1I2 (0.98) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL9489230 | 1.00 | NR1I2 (0.98) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL9489240 | 1.00 | NR1I2 (0.98) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL1706046 | 1.00 | NR1I2 (0.98) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL15971 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL9489265 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL13483263 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL20538862 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL9489255 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT | |
| Cefoxitin SCHEMBL3825166 | 0.99 | NR1I2 (1.00) | NR1I2PPARGTDP1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3687 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4101296-B1 | NORMOTHERMIC MACHINE ORGAN PERFUSION FLUID AND PREPARATION METHOD THEREFOR | BIOS CHANGZHOU BIOTECHNOLOGY CO LTD (CN) | 2026-04-15 | — | — | EP | claimed |
| CN-116812267-B | Cefoxitin sodium preparation system | 苏州盛达药业有限公司 | 2025-06-03 | — | — | CN | claimed |
| WO-2025111413-A1 | TREATMENT FOR SKIN DISORDERS | Mycotechnology, Inc. (US) | 2025-05-30 | — | — | WO | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| CN-119733055-A | Composition of beta-lactam inhibitor and cephalosporin medicine, and preparation method and application thereof | 福建泽瑞药业有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119735601-A | Superfine cefoxitin sodium and method for continuously preparing superfine cefoxitin sodium | 华北制药河北华民药业有限责任公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119331762-A | Bifidobacterium breve BX-18 and application thereof | 内蒙古农业大学 | 2025-01-21 | — | — | CN | claimed |
| US-20240282425-A1 | AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS | LOW GORDON KEITH (US) | 2024-08-22 | — | — | US | claimed |
| US-20240271178-A1 | METHOD FOR DETECTION OF ESCHERICHIA COLI AND ANTIBIOTIC RESISTANT BACTERIA IN WATER | Eastern Kentucky University (US) | 2024-08-15 | — | — | US | claimed |
| CN-118347974-A | Visual detection system and drug sensitivity test system for escherichia coli | 中南民族大学 | 2024-07-16 | — | — | CN | claimed |
| US-20020107265-A1 | EMULSION COMPOSITIONS FOR POLYFUNCTIONAL ACTIVE INGREDIENTS | LIPOCINE INC. | 2002-08-08 | — | — | US | claimed |
| EP-1210063-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | Lipocine, Inc. (US) | 2002-06-05 | — | — | EP | claimed |
| US-6309663-B1 | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents | LIPOCINE INC. | 2001-10-30 | — | — | US | claimed |
| US-6248363-B1 | Improved delivery of hydrophilic or hydrophobic pharmaceutical active ingredients, such as drugs, nutraceuticals, cosmeceuticals and diagnostic agents | LIPOCINE, INC. | 2001-06-19 | — | — | US | claimed |
| US-6245735-B1 | CONJUGATE OF ANTIBIOTIC AND POLYPEPTIDE OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR OR LIPOPOLYSACCHARIDE BINDING FRAGMENT | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2001-06-12 | — | — | US | claimed |
| WO-2001037808-A1 | SOLID CARRIERS FOR IMPROVED DELIVERY OF ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS | LIPOCINE, INC. (US) | 2001-05-31 | — | — | WO | claimed |
| WO-2001028555-A1 | EMULSION COMPOSITIONS FOR POLYFUNCTIONAL ACTIVE INGREDIENTS | LIPOCINE, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| WO-2001012155-A1 | COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS | LIPOCINE, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| EP-1051991-A2 | Apparatus for automatic administration of multiple doses of drugs | SARCOS, INC. (US) | 2000-11-15 | — | — | EP | claimed |
| US-6056734-A | Method for automatic dosing of drugs | SARCOS LC (US) | 2000-05-02 | — | — | US | claimed |