Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CETP | P11597 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.52 |
| ▸ | CCR6 | P51684 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | UBE2N | P61088 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4062277 | 1.00 | SPHK2 (0.52) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL4118327 | 1.00 | SPHK2 (0.52) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL11981278 | 1.00 | SPHK2 (0.52) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL11960050 | 1.00 | SPHK2 (0.52) | SPHK2SPHK1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11767806 | 0.91 | SPHK2 (0.58) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL10699276 | 0.91 | SPHK2 (0.62) | SPHK2SPHK1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11767811 | 0.91 | SPHK2 (0.58) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL17703964 | 0.91 | SPHK2 (0.62) | SPHK2SPHK1MEN1KMT2AMAPT | |
| SCHEMBL10699279 | 0.91 | SPHK2 (0.62) | SPHK2SPHK1MEN1KMT2AMAPT | |
| Acetic Acid SCHEMBL10698331 | 0.83 | MAPT (0.57) | SPHK2SPHK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236976-B2 | Processes for highly enantio- and diastereoselective synthesis of acyclic epoxy alcohols and allylic epoxy alcohols | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-08-07 | — | — | US | disclosed |
| US-20090163728-A1 | Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-06-25 | — | — | US | disclosed |
| WO-2005087755-A1 | PROCESSES FOR HIGHLY ENANTIO-AND DIASTEREOSELECTIVE SYNTHESIS OF ACYCLIC EPOXY ALCOHOLS AND ALLYLIC EPOXY ALCOHOLS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163728-A1 | Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols | ADH1C, ADH1A, ADH5 | SPHK2 572/4885SPHK1 803/4885MEN1 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.