SCHEMBL4118601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4116705	0.89	NOTUM (0.55)	ARGRM5NOTUMMEN1MAPT
	SCHEMBL19823672	0.80	AR (0.61)	ARGRM5NPSR1NPC1
	SCHEMBL6631125	0.79	NOTUM (0.57)	NOTUMNAMPTHSP90AA1HSP90AB1HSP90B1
	SCHEMBL2474223	0.79	AR (0.64)	ARGRM5NPSR1HSP90AA1MEN1
	SCHEMBL24416093	0.79	AR (0.60)	ARGRM5NPSR1MEN1KMT2A
	SCHEMBL6961137	0.78	NR1H2 (0.45)	ARGRM5NOTUMMEN1MAPT
	SCHEMBL4124255	0.78	GRM5 (0.49)	ARGRM5NAMPTNPC1RAB9A
	SCHEMBL4105991	0.78	NPC1 (0.56)	GRM5NOTUMMEN1MAPTKMT2A
	SCHEMBL4119191	0.78	RAB9A (0.56)	ARNOTUMMEN1MAPTKMT2A
	SCHEMBL12124653	0.76	AR (0.50)	ARGRM5NPSR1HSP90AA1VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.