⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919655 | 0.83 | — | — | |
| SCHEMBL18207547 | 0.74 | ADAM17 (0.33) | — | |
| SCHEMBL446335 | 0.73 | — | — | |
| SCHEMBL5761595 | 0.69 | GABRA1 (0.34) | — | |
| SCHEMBL5759308 | 0.69 | CHRM2 (0.36) | — | |
| SCHEMBL4764102 | 0.67 | ALDH1A1 (0.43) | — | |
| SCHEMBL2045954 | 0.64 | — | — | |
| SCHEMBL7905655 | 0.64 | — | — | |
| SCHEMBL467306 | 0.64 | — | — | |
| SCHEMBL128399 | 0.64 | NQO1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782565-B1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER IP GMBH (DE) | 2019-11-06 | — | — | EP | claimed |
| EP-2920163-B1 | PYRIDYLOXYAL ALKYL CARBOXAMIDES AND THEIR USE AS ENDOPARASITICIDES AND NEMATICIDE | BAYER CROPSCIENCE AG (DE) | 2018-05-02 | — | — | EP | claimed |
| US-9422276-B2 | Use of aryl and hetaryl carboxamides as endoparasiticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-23 | — | — | US | claimed |
| US-20140323736-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-30 | — | — | US | claimed |
| EP-2782565-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | claimed |
| WO-2013076230-A1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | claimed |
| US-20240109842-A1 | ACRYLAMIDE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-04-04 | — | — | US | disclosed |
| CN-114667280-A | Acrylamide compound | 大塚制药株式会社 | 2022-06-24 | — | — | CN | disclosed |
| WO-2021117733-A1 | ACRYLAMIDE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | WO | disclosed |
| EP-2782565-B1 | USE OF ARYL AND HETARYL CARBOXAMIDES AS ENDOPARASITICIDES | BAYER IP GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |
| EP-2920163-B1 | PYRIDYLOXYAL ALKYL CARBOXAMIDES AND THEIR USE AS ENDOPARASITICIDES AND NEMATICIDE | BAYER CROPSCIENCE AG (DE) | 2018-05-02 | — | — | EP | disclosed |
| US-9556121-B2 | Pyridyloxyalkyl carboxamides and use thereof as endoparasiticides and nematicides | BAYER CROPSCIENCE AG (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9422276-B2 | Use of aryl and hetaryl carboxamides as endoparasiticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| WO-2006103555-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-0375387-A2 | Amide compounds | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-06-27 | — | — | EP | disclosed |
| US-4895587-A | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0189774-B1 | PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0206251-B1 | HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0206251-A1 | Haloacetamide compounds, process for production thereof, and use thereof as herbicide | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |