Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359128 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNARAB9AHPGDMEN1 | |
| Trifluoroacetic Acid SCHEMBL3645313 | 0.82 | NPSR1 (0.40) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL1357926 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL31711004 | 0.73 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL166426 | 0.72 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL17076861 | 0.72 | ADORA2A (0.47) | SMN1; SMN2LMNARAB9ANPC1PKM | |
| SCHEMBL28262634 | 0.70 | ADORA2A (0.46) | LMNAPKMADORA2AADORA1 | |
| SCHEMBL1833232 | 0.70 | ADORA2A (0.49) | LMNAPKMADORA2AADORA1 | |
| SCHEMBL1703833 | 0.70 | ADORA2A (0.53) | LMNAHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL3081863 | 0.70 | ADORA2A (0.49) | LMNARAB9AHPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, GPR119 | SMN1; SMN2 1719/4885LMNA 2277/4885RAB9A 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.