Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107794 | 0.87 | CDK1 (0.42) | CDK1NPSR1HSD17B10HTTKDM4E | |
| SCHEMBL3984145 | 0.77 | CDK1 (0.60) | MEN1KMT2ACDK1EGFRCDK4 | |
| SCHEMBL4131075 | 0.73 | CTSC (0.56) | MAPTEGFRPOLBLMNASMN1; SMN2 | |
| SCHEMBL3769145 | 0.73 | WEE1 (0.62) | EGFRIGF1R | |
| Hydrochloric Acid SCHEMBL10002647 | 0.72 | MAPT (0.53) | MEN1KMT2ANPSR1HSD17B10HTT | |
| SCHEMBL6675253 | 0.70 | MEN1 (0.62) | MEN1KMT2ACDK1EGFRIGF1R | |
| SCHEMBL13002653 | 0.70 | NPSR1 (0.53) | MEN1KMT2ANPSR1HSD17B10HTT | |
| SCHEMBL21672280 | 0.70 | FGFR4 (0.51) | NPSR1HTTKDM4EMAPTHPGD | |
| SCHEMBL29215757 | 0.70 | MEN1 (0.49) | MEN1KMT2ACDK1EGFRIGF1R | |
| SCHEMBL1391444 | 0.70 | POLB (0.47) | MEN1KMT2ACDK1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063240-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF AURORA KINASE | ARROW THERAPEUTICS LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |