Dimethylamine

Dimethylamine

SCHEMBL4120738

CNC.Cc1c(OCC2(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 2/20 0.38
KDR P35968 1/20 0.38
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
ACHE P22303 3/20 0.37
GNRHR P30968 1/20 0.35
BCHE P06276 2/20 0.35
GPR119 Q8TDV5 6/20 0.34
MERTK Q12866 1/20 0.34
HTR6 P50406 1/20 0.34
FAAH O00519 1/20 0.33
KDM1A O60341 1/20 0.33
YAP1 P46937 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL4126948 0.94 ACHE (0.38) ACHEBCHE
SCHEMBL4127230 0.90 ACHE (0.37) CSF1RKDRKDM4EPKMACHE
Dimethylamine SCHEMBL4134245 0.89 GPR119 (0.38) CSF1RKDRKDM4EPKMACHE
SCHEMBL4120736 0.89 ACHE (0.36) CSF1RKDRKDM4EPKMACHE
Dimethylamine SCHEMBL4128055 0.88 CSF1R (0.39) CSF1RKDRKDM4EPKMACHE
Dimethylamine SCHEMBL4125647 0.85 CSF1R (0.42) CSF1RKDRKDM4EPKMACHE
Dimethylamine SCHEMBL4119922 0.83 ACHE (0.46) CSF1RKDRKDM4EPKMACHE
SCHEMBL4112133 0.83 ACHE (0.38) ACHEBCHE
SCHEMBL4126940 0.82 ACHE (0.38) ACHEBCHE
Dimethylamine SCHEMBL4120781 0.82 ACHE (0.41) ACHEBCHEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318690-A1 Benzisoxazole Compound EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-12-24 US disclosed
EP-2017275-A1 BENZISOXAZOLE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2009-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090318690-A1 Benzisoxazole Compound NR1I2, NR1I3, NR0B1 CSF1R 628/4885KDR 3127/4885KDM4E 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.