Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | YAP1 | P46937 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4114208 | 0.91 | ACHE (0.49) | ACHEBCHE | |
| Dimethylamine SCHEMBL4122314 | 0.90 | GPR119 (0.43) | ACHEYAP1GPR119 | |
| Dimethylamine SCHEMBL4122129 | 0.90 | GPR119 (0.41) | ACHEKDM4EPKMCSF1RKDR | |
| Dimethylamine SCHEMBL4131682 | 0.90 | KDM4E (0.46) | ACHEKDM4EPKMCSF1RBCHE | |
| Dimethylamine SCHEMBL4129875 | 0.89 | PDCD1 (0.42) | ACHEYAP1CSF1RBCHEKDR | |
| Dimethylamine SCHEMBL4127332 | 0.89 | EPHA2 (0.42) | ACHEYAP1CSF1RBCHEKDR | |
| Dimethylamine SCHEMBL4126290 | 0.89 | CSF1R (0.45) | ACHEKDM4EPKMCSF1RKDR | |
| Dimethylamine SCHEMBL4133492 | 0.88 | LMNA (0.41) | ACHEKDM4EPKMCSF1RKDR | |
| SCHEMBL13596402 | 0.88 | ACHE (0.46) | ACHEYAP1KDM4EPKMCSF1R | |
| Dimethylamine SCHEMBL4121737 | 0.88 | GPR119 (0.39) | ACHEKDM4EPKMCSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885YAP1 3743/4885KDM4E 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.